Analysis of Hair Steroid Hormone Concentrations at Different Parts of the Head by Liquid Chromatography-Tandem Mass Spectrometry

    October 2021 in “ Clinica Chimica Acta ”
    Yoshitaka Hobo, Jun Nishikawa, Yoshimichi Miyashiro, Akira Fujikata
    Studysummary This study found that higher levels of dihydrotestosterone in the parietal region of the scalp may correlate with the clinical presentation of androgenetic alopecia.
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    Research cited in this study 14

    1. Measurement of Steroid Hormones by Liquid Chromatography-Tandem Mass Spectrometry with Small Amounts of Hair Steroids · 2020
    2. Serum Levels of Androgen-Associated Hormones Are Correlated with Curative Effect in Androgenic Alopecia in Young Men Medical Science Monitor · 2018
    3. Determinants of Hair Cortisol and Hair Cortisone Concentrations in Adults Psychoneuroendocrinology · 2015
    4. Gas Chromatography/Mass Spectrometry Based Hair Steroid Profiling May Reveal Pathogenesis in Hair Follicles of the Scalp Rapid communications in mass spectrometry/RCM. Rapid communications in mass spectrometry · 2011
    5. Molecular Basis of Androgenetic Alopecia: From Androgen to Paracrine Mediators Through Dermal Papilla Journal of Dermatological Science · 2010
    6. The Hair Follicle as a Dynamic Mini-Organ Current Biology · 2009
    7. Measurement of Cortisol in Human Hair as a Biomarker of Systemic Exposure Clinical and investigative medicine · 2007
    8. The Importance of Dual 5α-Reductase Inhibition in the Treatment of Male Pattern Hair Loss: Results of a Randomized Placebo-Controlled Study of Dutasteride Versus Finasteride Journal of The American Academy of Dermatology · 2006
    9. Androgen Action on Human Skin – From Basic Research to Clinical Significance Experimental dermatology · 2004
    10. Current and Novel Methods for Assessing Efficacy of Hair Growth Promoters in Pattern Hair Loss Journal of The American Academy of Dermatology · 2003
    11. Androgens and Alopecia Molecular and Cellular Endocrinology · 2002
    12. Serum Androgens and Genetic Linkage Analysis in Early Onset Androgenetic Alopecia Journal of Investigative Dermatology · 1999
    13. Different Levels of 5α-Reductase Type I and II, Aromatase, and Androgen Receptor in Hair Follicles of Women and Men with Androgenetic Alopecia Journal of Investigative Dermatology · 1997
    14. Androgen Metabolism as It Affects Hair Growth in Androgenetic Alopecia Dermatologic Clinics · 1996

    Related research 1

    1. Age-Dependent Regulation by Androgens of Gene Expression in the Anterior Hypothalamus and Stress-Induced Release of Adrenal Hormones in Adolescent and Adult Male Rats Journal of neuroendocrinology · 2019