Age-Dependent Regulation by Androgens of Gene Expression in the Anterior Hypothalamus and Stress-Induced Release of Adrenal Hormones in Adolescent and Adult Male Rats

    March 2019 in “ Journal of neuroendocrinology ”
    Matthew R. Green, Mostafa Zeidan, Travis E. Hodges, Cheryl M. McCormick
    Studysummary This study found that developmental changes in testosterone synthesis and gene regulation may explain age differences in corticosterone release in response to stress between adolescent and adult rats.
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    Research cited in this study 1

    1. Central 5-Alpha Reduction of Testosterone Is Required for Testosterone's Inhibition of the Hypothalamo-Pituitary-Adrenal Axis Response to Restraint Stress in Adult Male Rats Brain Research · 2013