January 2025 in “Journal of Contemporary Medical Practice” The researchers reported that nano-cerium oxide improved androgenetic alopecia in mice by increasing the ratio of terminal to vellus hairs, elevating IGF-1 expression, and reducing TGF-β and DHT levels in the skin, suggesting potential for drug development.
September 2024 in “International Journal of Pharmaceutical Quality Assurance” This review outlines the potential of nanoemulsion-based hydrogels (nanoemulgels) for enhanced topical and transdermal drug delivery in treating skin disorders, highlighting their ability to improve therapeutic efficacy, control drug release, and boost patient compliance.
January 2026 in “Microsystems & Nanoengineering” This study analyzed 853 articles to reveal that research on silica-based nanobiomaterials in regenerative medicine has rapidly increased, with distinct regional differences in impact and emerging focus areas in drug delivery and wound healing.
19 citations
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January 2015 in “International Journal of Cosmetic Science” This study reports that optimized PLA nanoparticles can effectively target hair follicles to deliver both lipophilic and hydrophilic compounds, suggesting potential applications in hair cosmetics and treatments.
15 citations
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March 2021 in “Journal of Nanobiotechnology” This study developed a nanoscale biomimetic matrix that effectively and stably expands human hair follicle stem cells, offering a new tool for hair follicle reconstruction research.
25 citations
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February 2024 in “Pharmaceutics” This article outlines how nanotechnology strategies, including phospholipid-based nanocarriers like liposomes, could enhance the effectiveness and skin tolerability of acne treatments, aiming to reduce side effects and improve patient compliance in managing acne vulgaris.
30 citations
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November 2015 in “Advanced Pharmaceutical Bulletin” This study found that nanoethosomes containing Lidocaine showed effective skin penetration, suggesting they may be a suitable carrier for topical anesthetic delivery.
3 citations
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February 2023 in “Journal of drug delivery science and technology” In vitro, this study found that PTX and HU SF-FA NLCs showed greater cytotoxicity and apoptosis in ovarian cancer cells than pure paclitaxel, suggesting promise as a targeted drug delivery platform.
January 2025 in “New Journal of Chemistry” In this study, researchers developed hollow mesoporous organosilica nanoparticles and confirmed their synthesis using IR spectroscopy, then evaluated the nanoparticles for endocytosis and biocompatibility, although specific results of these tests are not reported in the abstract.
40 citations
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January 2022 in “Frontiers in Chemistry” This study found that a microneedle array patch using a blend of kangfuxin, chitosan, and fucoidan significantly accelerated wound healing in rats by enhancing epithelial thickness and collagen deposition.
57 citations
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September 2017 in “Journal of controlled release” This review discusses recent advances in using nanocarrier-loaded gels for various medical applications and reports no new clinical results, highlighting potential advantages in therapeutic strategies.
45 citations
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March 2020 in “International Journal of Nanomedicine” This study found that nanoemulsion-based formulations, such as nanoemulgel and NFs, might serve as promising topical delivery systems for treating inflammatory diseases, potentially offering an alternative to traditional nonsteroidal anti-inflammatory drugs, which are associated with adverse effects.
1 citations
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February 2026 in “ACS Nano” This study developed the TLMG hydrogel, a seamless in situ biointerface platform, demonstrating robust adhesion, high conductivity, and therapeutic effects for intelligent wound management in complex animal models and human tests, indicating its promise for integrated bioelectronic medicine.
1 citations
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September 2025 in “Scientific Reports” This study reported that a colistin sulfate-loaded nanoemulgel showed improved antimicrobial activity and skin permeability compared to a CS solution, suggesting a potential new approach for treating severe infections caused by multidrug-resistant bacteria.
November 2025 in “ACS Applied Materials & Interfaces” This study found that in a mouse model of androgenetic alopecia, topical application of finasteride-loaded Platycladi cacumen-derived nanovesicles improved hair regrowth more effectively than minoxidil.
1 citations
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November 2020 in “Asian Journal of Pharmaceutical and Clinical Research” This review discusses the potential of nanotechnology in treating idiopathic pulmonary fibrosis by targeting abnormal alveolar epithelial cells and reports no new clinical results.
6 citations
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June 2025 in “Nano Biomedicine and Engineering” This source reports on advances in stimulus-responsive nanoparticle-based PROTACs (nano-PROTACs), which aim to overcome existing challenges like poor cell permeability and systemic off-target effects by enabling controlled protein degradation through endogenous or exogenous stimuli, potentially enhancing therapeutic efficacy and reducing toxicity.
8 citations
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May 2025 in “Biomimetics” In this review, cellulose-based nanofibers are highlighted for their potential in wound care, given their biodegradability, biocompatibility, and ability to enhance antimicrobial properties and drug delivery in wound dressings through modern fabrication techniques like electrospinning.
November 2025 in “OPAL (Open@LaTrobe) (La Trobe University)” This study found that transdermal delivery of finasteride using biomimetic Platycladi cacumen-derived nanovesicles enhanced hair regrowth in a mouse model of androgenetic alopecia, outperforming minoxidil by improving skin permeation, reducing oxidative stress, and boosting local drug retention.
10 citations
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January 2020 in “Journal of Materials Chemistry B” This study developed a biodegradable nanofibrous biofilm that attracts skin-related cells and accelerates blood vessel formation, potentially improving skin wound healing.
January 2026 in “International Journal of Applied Pharmaceutics” This review discusses the integration of nanoparticles with microneedles to improve drug delivery through enhanced stability, bioavailability, and controlled release, noting ongoing challenges with stability, scalability, and safety.
January 2015 in “SciDok (Saarland University and State Library)” This study confirmed the porcine ear skin model's effectiveness for studying nanoparticle-based drug delivery in human hair follicles, noting particle-dependent uptake and enhancement by massage.
12 citations
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March 2023 in “Pharmaceutics” In this study, researchers developed microparticle-embedded gas-propelled microneedles that showed higher drug loading and transdermal delivery efficiency compared to traditional microneedles.
June 2026 in “Clay Minerals” In this review, researchers highlighted the potential of clay minerals like kaolinite and zeolite as promising haemostatic materials, due to properties such as high water absorption and good biocompatibility, while discussing their current advances and the importance of integrating multifunctional capabilities for future wound dressings.
29 citations
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September 2020 in “Polymers” This study found that electrospun poly(ε-caprolactone)/poly(3-hydroxybutyrate) blend fibers demonstrated nanometric dimensions and promising properties for drug delivery, with curcumin release linked to fiber morphology and processing parameters.
19 citations
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January 2022 in “Journal of Nanomaterials” This study concluded that an adapalene nanohydrogel containing Tween-80 could be a promising and stable topical treatment option for acne vulgaris due to enhanced skin permeability and stability compared to other formulations.
24 citations
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February 2021 in “Polymers” This study found that urchin-like Ag–Au bimetallic and Ag nanoparticle-decorated PAN mats showed significant antibacterial effects and potential for wound healing in in vitro and in vivo animal models.
December 2013 in “Biomedical and biopharmaceutical research” This review discusses technological advances in liposome systems for drug delivery and reports no new clinical results; it highlights the clinical acceptance and market presence of liposomal products.
January 2018 in “Refubium (Universitätsbibliothek der Freien Universität Berlin)” In this study, researchers tested various nanocarrier characteristics and found they could enhance drug delivery to specific skin areas and immune cells, potentially improving treatments for skin conditions by targeting drugs effectively.
65 citations
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March 2022 in “Molecules” This study examines the role of nanotechnology in cosmetics, highlighting its benefits in improving ingredient solubility and stability, but also noting challenges such as cost, shelf life, and safety concerns, along with regulatory complexities, particularly in harmonizing global legislation.