Data-Driven Visualization of Silica-Based Nanobiomaterial Dynamics for Tissue Regeneration

    January 2026 in “ Microsystems & Nanoengineering
    Chao Yang, Z. P. Xie, Sihua Liang, Zhan Liu, Luís Cardoso, Dan Hou, Janak Lal Pathak, Lü Li
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    Studysummary This study analyzed 853 articles to reveal that research on silica-based nanobiomaterials in regenerative medicine has rapidly increased, with distinct regional differences in impact and emerging focus areas in drug delivery and wound healing.
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    The study systematically analyzed 853 research articles on silica-based nanobiomaterials (SNs) from 2006 to 2025, using bibliometric tools to visualize trends and research hotspots in regenerative medicine. It found a rapid increase in research output, with China leading in volume and the United States excelling in citation impact. Key research areas include drug delivery systems, antimicrobial activity, bone regeneration, and wound healing, with emerging topics like mesoporous bioactive glass nanoparticles and zinc ion dopants. The study highlights disparities in research impact and offers insights into future directions and challenges in the field.
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