8 citations
,
January 2020 in “Skin appendage disorders” This review found that supplements containing saw palmetto may improve hair quality and density in patients with androgenetic alopecia and telogen effluvium, but more large-scale RCTs are needed for conclusive evidence.
8 citations
,
November 2019 in “International Journal of Pharmaceutics” This work explores using a liquid crystalline phase to stabilize benzoyl peroxide nanosuspensions, suggesting a promising method to potentially reduce the side effects of acne treatments.
8 citations
,
January 2019 in “Nanomedicine” This commentary reviews the application of pharmaceutical nanotechnology in Egypt, highlighting promising developments and diverse drug-delivery approaches, but reports no new research findings.
8 citations
,
April 2017 in “American Journal of Dermatopathology” In this study, nail matrix pathology in a patient with Cronkhite–Canada Syndrome revealed matrix hypergranulosis, suggesting that an inflammatory process may play a key role in the condition's pathogenesis.
8 citations
,
April 2012 in “Laser Physics Letters” This study found that a curcumin-labeled particle-associated antiseptic penetrated deeper into hair follicles in porcine skin than particles without antiseptic.
8 citations
,
April 2010 in “JEADV. Journal of the European Academy of Dermatology and Venereology/Journal of the European Academy of Dermatology and Venereology” This case report details the first pediatric occurrence of naevus trichilemmocysticus, a newly defined type of organoid naevus.
7 citations
,
August 2025 in “Journal of Nanobiotechnology” This review highlights the potential of microneedles and nanomedicine in advancing tissue regeneration, emphasizing their innovative, localized, and minimally invasive approaches as promising solutions to current challenges in treating chronic wounds and degenerative diseases.
7 citations
,
January 2025 in “ACS Applied Materials & Interfaces” This study developed a zinc-infused egg white and GelMA hydrogel that enhanced cellular processes crucial for wound healing, including fibroblast proliferation and collagen expression, and demonstrated promising biocompatibility and bioactivity in vivo, suggesting potential effectiveness in repairing damaged tissues.
7 citations
,
May 2023 in “Nanomaterials” In this study on Danio rerio, researchers found that exposure to titanium dioxide nanoparticles did not affect embryonic development but altered the structure of male gonads, acting as potential endocrine disruptors with androgenic activity.
7 citations
,
August 2022 in “Journal of Nanobiotechnology” This review discusses recent advances in stimuli-responsive nanoformulations for CRISPR-Cas9 delivery, highlighting their design rationales and potential biomedical applications, but reports no new experimental results.
7 citations
,
December 2021 in “Pharmaceutics” This review examines the anti-alopecia effects of plant-derived phytochemicals and their mechanisms for promoting hair growth, but it reports no new clinical findings.
7 citations
,
April 2020 in “Curēus” In this pilot study, both microneedling and CO2 laser combined with hair transplantation and nbUVB demonstrated potential for inducing repigmentation in refractory palmar-plantar vitiligo, though further research is needed to ascertain their relative efficacy.
7 citations
,
October 2024 in “Drug Delivery and Translational Research” In this study, using an ex vivo porcine skin model, researchers found that a 4% nanoparticle concentration significantly enhanced the transport of fluorescein sodium into hair follicles compared to a 2% concentration, while higher concentrations did not further increase penetration depth.
7 citations
,
June 2024 in “Skin Research and Technology” Combining treatments significantly reduces dark circles and wrinkles better than nanofat alone.
7 citations
,
December 2022 in “Frontiers in Bioengineering and Biotechnology” This review discusses the role of extracellular vesicles as therapeutic agents for wound healing and highlights the need for further research into their clinical applications.
7 citations
,
July 2022 in “Pharmaceutics” This study found that a dissolvable microneedle device delivering rapamycin and epigallocatechin gallate nanoparticles significantly enhanced hair regrowth in C57BL/6 mice within 7 days, demonstrating increased hair shaft growth and follicle density with minimal inflammation compared to untreated mice.
7 citations
,
January 2022 in “Bioengineering” This study found that a lipid-based nanoparticle formulation with oleic acid for delivering dutasteride showed lower skin permeation compared to a formulation without oleic acid, indicating its potential for targeted dermal delivery.
7 citations
,
December 2021 in “Pharmaceutics” This study developed a nanoemulsion of garlic oil and apple cider vinegar loaded with minoxidil to enhance drug permeation through skin, reporting improved ex vivo skin permeation parameters compared to an aqueous dispersion of minoxidil, suggesting potential benefits for treating alopecia areata.
7 citations
,
August 2021 in “ChemEngineering” This study found that Soluplus and L-ascorbyl 2,6-dipalmitate nanoparticles may improve minoxidil's skin permeability through stable hydrophobic interactions, enhancing its potential for targeted skin application.
7 citations
,
June 2021 in “Journal of Cosmetic Dermatology” This study concluded that among 11 formulations tested, the herbal shampoo formulation H2, containing fermented Cyclea peltata, had superior organoleptic and physicochemical properties.
7 citations
,
July 2018 in “International Journal of Applied Pharmaceutics” This study found that optimizing chitosan-tripolyphosphate nanoparticles can enhance the sustained percutaneous delivery of caffeine, with certain conditions affecting stability and release rates.
7 citations
,
January 2017 in “Journal of Clinical Biochemistry and Nutrition” This study found that vitamin D was positively associated with serum ferritin levels in Korean women without metabolic syndrome, but this association was not observed in those with metabolic syndrome.
7 citations
,
September 2011 in “International Journal of Dermatology” This study investigated demographic and clinical characteristics of twenty-nail dystrophy in Korea, identifying differences in subtype and gender predominance between children and adults.
7 citations
,
January 1990 in “Clinical and Experimental Dermatology” This study observed that without any treatment, hair counts did not increase, suggesting that counting methods are unlikely to explain the 'placebo-effect' seen in previous minoxidil studies.
6 citations
,
February 2025 in “International Journal of Molecular Sciences” This study found that the solid self-nanoemulsifying drug delivery system improved the oral bioavailability of carvedilol significantly compared to the drug alone, enhancing its solubility, dissolution, AUC, and Cmax.
6 citations
,
August 2020 in “Journal of Pharmaceutical Innovation” This study found that a lipid nanoemulsion-based gel of finasteride for topical use improved hair growth and was effective against alopecia, with slow skin permeation and increased efficacy compared to a testosterone-treated group.
6 citations
,
June 2025 in “Nano Biomedicine and Engineering” This source reports on advances in stimulus-responsive nanoparticle-based PROTACs (nano-PROTACs), which aim to overcome existing challenges like poor cell permeability and systemic off-target effects by enabling controlled protein degradation through endogenous or exogenous stimuli, potentially enhancing therapeutic efficacy and reducing toxicity.
6 citations
,
January 2025 in “Molecules” This review highlights the challenges in developing nano-scale drug delivery systems for natural antioxidants in wound healing, pointing out issues like low solubility and skin permeability, and discusses potential solutions such as combining polymers and lipids to enhance delivery effectiveness.
6 citations
,
June 2024 in “Drug Testing and Analysis” This review reports on the use of nails as an alternative biological matrix to hair for assessing long-term drug consumption, emphasizing that while there are clear differences between nail and hair samples, more standardized research is necessary for definitive conclusions.
6 citations
,
April 2024 in “Health Science Reports” This study found that young patients with severe AA are more prone to nail abnormalities such as pitting and leukonychia, with koilonychia and red spots lunula in more severe cases.