10 citations
,
February 2022 in “Pharmaceuticals” This study found that smaller curcumin nanocrystals (60 nm) enhanced transdermal and transfollicular penetration more effectively than larger sizes, influenced by particle size.
10 citations
,
July 2021 in “European journal of pharmaceutics and biopharmaceutics” This study reported that larger caffeine nanocrystals, at 694 nm, increased caffeine bioavailability via transfollicular penetration compared to smaller nanocrystals, especially in long-term serum concentration measurements.
10 citations
,
February 2021 in “International Journal of Nanomedicine” This study found that a chitosan-decorated finasteride nanosystem exhibited satisfactory drug release and retention in rat skin, suggesting it could enhance topical delivery for androgenic alopecia treatment.
10 citations
,
January 2021 in “BioMed Research International” This study found that patients who recovered from COVID-19 experienced various skin, hair, and nail issues, with hair shedding being more common in those with moderate to severe cases.
10 citations
,
May 2020 in “Advances in Polymer Technology” This study found that melatonin-loaded nanoparticles improved antidepressant effects and HPA axis regulation in pinealectomized rats, compared to free melatonin, through controlled-release properties.
10 citations
,
January 2020 in “Journal of Materials Chemistry B” This study developed a biodegradable nanofibrous biofilm that attracts skin-related cells and accelerates blood vessel formation, potentially improving skin wound healing.
10 citations
,
August 2016 in “Anais brasileiros de dermatologia/Anais Brasileiros de Dermatologia” This study found that nail abnormalities, particularly longitudinal ridging, were more frequent in vitiligo patients (78%) compared to healthy controls (55%).
10 citations
,
May 2016 in “Polymer” This study reports that novel core-ABS nanocarriers efficiently loaded with dexamethasone and finasteride show potential for dermal drug delivery, exhibiting non-toxic interactions with human keratinocyte cells and skin penetration.
10 citations
,
February 2008 in “International Journal of Andrology” This study found that a 400-mg dose of oral testosterone with dutasteride increases serum testosterone levels for 8–10 hours in hypogonadal men, with the nanomilled formulation unaffected by food, suggesting a practical twice-daily therapy option.
10 citations
,
June 2001 in “International Journal of Cosmetic Science” This study found that laboratory-formulated natural shampoos condition hair better than commercial herbal shampoos, as shown by SEM micrograph analysis of hair microstructure.
10 citations
,
January 2001 in “Bioscience Biotechnology and Biochemistry” This study found that partial protein extraction from keratinized tissues, such as hair and nails, reveals protein patterns distinct from whole protein extracts, including the presence of ubiquitin.
9 citations
,
June 2019 in “Archives of Dermatological Research” This study found that both topical calcipotriol and narrow band ultraviolet B phototherapy improved hair regrowth and vitamin D3 levels in alopecia areata patients.
9 citations
,
September 2022 in “Pharmaceutics” This study found that porcine-placenta-extract-loaded nanoformulated serum improved skin hydration and promoted hair growth, as well as reduced intracellular ROS and inflammation without cytotoxicity in human subjects.
9 citations
,
February 2022 in “European Journal of Pharmaceutics and Biopharmaceutics” This study suggests that a nanostructured lipid carrier formulation delivering minoxidil and latanoprost may enhance effectiveness and tolerability in treating alopecia by targeting hair follicles.
9 citations
,
October 2021 in “Biological and Pharmaceutical Bulletin” This study found that mupirocin nanoparticle-loaded hydrogel was safe and more effective for healing burn wounds in rats compared to mupirocin ointment, showing promise for future clinical trials.
9 citations
,
January 2021 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found a persistent gender gap in NIH dermatology research funding from 2015 to 2019, with male recipients obtaining the majority of the funding.
9 citations
,
October 2018 in “Elsevier eBooks” This article discusses how challenges in drug development and success rates are driving a shift in the pharmaceutical industry towards engineering targeted drug delivery systems, with nanomaterials offering potential solutions for selective therapeutic delivery.
9 citations
,
April 2018 in “Journal of Dermatological Treatment” This study found that oral tofacitinib monotherapy improved nail changes in 73.3% of adults with moderate-to-severe alopecia areata over a median period of 5 months, but nail improvement was not linked to the severity of hair loss or hair regrowth.
9 citations
,
December 2015 in “Journal of Dermatological Case Reports” A 12-year-old with ichthyosis linearis circumflexa showed significant improvement after 30 sessions of narrowband UVB phototherapy, as reported in this case study.
9 citations
,
October 2008 in “British Journal of Dermatology” This case report describes a patient with primary cutaneous natural killer/T-cell lymphoma, nasal type, where monoclonal Epstein–Barr virus genome expansion was associated with terminal aggressive behavior after an indolent clinical course.
9 citations
,
June 2001 in “International Journal of Cosmetic Surgery and Aesthetic Dermatology” This paper describes a systematic approach to creating a natural hairline in one session using modern hairline design principles and reports no new clinical results.
8 citations
,
December 2021 in “Military Medical Science Letters” This review highlights the potential of nanoemulgel as a promising drug delivery system for lipophilic drugs, but presents no new experimental results; it discusses composition, preparation methods, and applications.
8 citations
,
May 2021 in “Applied Materials Today” This study found that Cur-Fe-mesoporous silica nanoparticles synergistically inhibited scar formation and promoted hair follicle regeneration in skin burn wound healing by releasing bioactive components like SiO32−, Fe3+, and Fe-Cur chelates.
8 citations
,
March 2025 in “Journal of Drug Delivery Science and Technology” Dissolvable microneedles are a promising, painless method for effective skin treatments.
8 citations
,
May 2024 in “Advanced NanoBiomed Research” This review examines advancements in lipid and inorganic nanocarriers, such as liposomes and inorganic nanoparticles, for transdermal drug delivery, noting enhanced absorption and stability but acknowledging that few have reached clinical use.
8 citations
,
September 2023 in “Advanced Pharmaceutical Bulletin” In a double-blind clinical trial, this study found that a gel containing chitosan-coated spironolactone nanoparticles effectively reduced acne lesions over 8 weeks without adverse skin effects, suggesting potential for enhanced acne treatment through targeted skin delivery.
8 citations
,
June 2023 in “Journal of clinical medicine” This study reviews the use of nanofat in facial rejuvenation and cosmetic surgery, highlighting its potential for improving skin appearance and treating conditions like wrinkles and acne scars, yet emphasizes the need for further research into its long-term efficacy and safety.
8 citations
,
May 2021 in “Journal of the European Academy of Dermatology and Venereology” This case report describes a 23-year-old male patient with nail discoloration that may be associated with COVID-19, suggesting possible microvascular damage.
8 citations
,
January 2021 in “Pharmaceutics” This study found that using nanoporous silica entrapped lipid-drug complexes enhanced the solubility and bioavailability of dutasteride in beagle dogs.
8 citations
,
October 2020 in “Pharmaceutics” This study explored using a chitosan oligomer coating for topical delivery of dutasteride-loaded nanostructured lipid carriers, aiming to reduce systemic exposure and cytotoxicity.