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Finasteride in male rats causes liver and metabolic issues in their offspring.

Kennedy's disease leads to muscle weakness without a cure, but exercise and managing symptoms may help patients live a normal lifespan.

Immune cells around hair follicles help control hair growth and could be targets for treating hair disorders.

Early diagnosis and aggressive treatment are key for managing rare scalp disorders that cause permanent hair loss.

ADAM 10 and ADAM 12 proteins are involved in different stages of hair growth and could be targets for treating hair disorders.

Valproic acid can cause muscle damage and liver issues, which improve after stopping the drug.

Lower levels of certain genes in hair cells improve hair loss treatment outcomes.

Gene therapy shows promise for treating skin disorders and cancer, but faces technical challenges.

Three siblings with a rare genetic condition had abnormal sexual development and chose different gender identities, needing surgery and therapy.

Cicatricial alopecia, a permanent hair loss condition, is mainly caused by damage to specific hair follicle stem cells and abnormal immune responses, with gene regulator PPAR-y and lipid metabolism disorders playing significant roles.

MK-0773 safely increased muscle mass but did not improve muscle strength or function in elderly women with sarcopenia.

Hidradenitis suppurativa may be related to hormones and patients often have metabolic disorders; more research is needed to understand this connection.

Changes in testosterone and estrogen receptor genes can affect how men age, influencing body fat, hair patterns, and possibly leading to skin disorders.

Nandrolone might increase muscle mass with fewer side effects than testosterone but could cause erectile dysfunction and needs more research.

Transgender youth have more sleep disorders, but gender-affirming therapy may help reduce them.

Natural gene therapy shows promise for treating skin disorders like epidermolysis bullosa.

Chromosomal differences affect how muscle cells respond to testosterone.

All women with Polycystic Ovary Syndrome (PCOS) in a study had at least one skin disorder, with the most common being excessive hair growth, acne, dark skin patches, hair loss, and oily skin.

Certain vitamins in wrong amounts, alcohol abuse, metals, and other toxins can cause serious brain and nerve damage.

The document concludes that Syndromes of Severe Insulin Resistance are rare disorders with limited treatment options.

Epidermolysis bullosa simplex causes easily blistered skin due to faulty skin cell proteins, leading to new treatment ideas.

The AUTS2 gene is linked to neurological disorders and may affect human brain development and cognition.

There are many treatments for permanent hair loss disorders, but their effectiveness varies and there's no clear best option.

Hormone imbalances can cause specific skin changes, which may help in early detection of endocrine disorders.

Sex hormone treatments can increase muscle mass in older adults but have inconsistent effects on muscle function and may carry cardiovascular risks.

New androgen receptor modulators show promise for treating diseases like prostate cancer and muscle wasting.

Overweight women with PCOS are more likely to have excess male hormones.

The document concludes that periocular hair disorders have various causes and treatments, and proper evaluation by specialists is important for management and prognosis.

The book provides updated knowledge on hair disorders and new treatments for hair loss.

Cadmium chloride pollution can cause skin disorders, speed up aging, and prevent hair growth.