50 citations
,
February 2013 in “BMC evolutionary biology” Cetaceans lost hair due to changes in the Hr and FGF5 genes.
49 citations
,
September 2014 in “Journal of Investigative Dermatology” Using the drugs AMD3100 and Tacrolimus together greatly improves skin healing and hair growth after a deep skin cut by increasing stem cells in the wound.
44 citations
,
January 2015 in “Development” Human Schwann cells can be quickly made from hair follicle stem cells for nerve repair.
37 citations
,
June 2019 in “Stem cells” Special particles from skin cells can promote hair growth by activating a specific growth signal.
35 citations
,
March 2010 in “BMC veterinary research” Goats with BSE or scrapie show varying symptoms, and using only clinical signs may not detect all scrapie cases.
34 citations
,
September 2020 in “Clinical, cosmetic and investigational dermatology” Hyaluronic acid increases collagen synthesis safely, while poly-L-lactic acid may cause complications by affecting fibroblasts.
31 citations
,
November 2012 in “Journal of biological chemistry/The Journal of biological chemistry” The right amount of retinoic acid is essential for normal hair growth and development.
27 citations
,
March 2008 in “Cell stress & chaperones” Localized heat or specific injections can prevent chemotherapy-induced hair loss without affecting cancer treatment.
26 citations
,
July 2011 in “PubMed” Treating H. pylori infection might help cure alopecia areata.
26 citations
,
November 2008 in “Clinical endocrinology” The document concludes that more multidisciplinary research is needed to understand and treat PCOS, a condition that significantly affects women's health and quality of life.
24 citations
,
May 2018 in “Indian Journal of Dermatology, Venereology and Leprology” 24 citations
,
March 2009 in “Fertility and sterility” Pioglitazone improved insulin sensitivity and altered cortisol metabolism in PCOS patients.
23 citations
,
December 2021 in “Frontiers in Immunology” IL-1 family cytokines are crucial for skin defense and healing, but their imbalance can cause skin diseases.
23 citations
,
September 2021 in “Frontiers in Cellular and Infection Microbiology” Testosterone's effects on COVID-19 are unclear and need more research.
22 citations
,
November 2016 in “International journal of molecular sciences” Vitamin D receptor is important for regulating hair growth and wound healing in mice.
20 citations
,
November 2021 in “Frontiers in cell and developmental biology” Skin organoids from stem cells could better mimic real skin but face challenges.
16 citations
,
April 2021 in “Frontiers in Cell and Developmental Biology” 15 citations
,
December 2021 in “Pharmaceutics” The study found key factors in the cause of hidradenitis suppurativa, its link to other diseases, and identified existing drugs that could potentially treat it.
15 citations
,
December 2006 in “Clinical interventions in aging” 5 alpha-reductase inhibitors like finasteride may lower prostate cancer risk and improve cancer screening.
14 citations
,
May 2016 in “Mechanisms of Development” Basonuclin 2 is vital for the development of facial bones, hair follicles, and male germ cells in adult mice, and its absence can lead to dwarfism and abnormal follicles.
14 citations
,
April 2016 in “PloS one” The KRTAP11-1 gene promoter is crucial for specific expression in sheep wool cortex.
13 citations
,
September 2022 in “Frontiers in immunology” Ifidancitinib, a JAK inhibitor, effectively regrows hair in mice with alopecia by tiring out harmful T cells.
13 citations
,
May 2019 in “Actas Dermo-Sifiliográficas” Vitamin D is important for skin health, but more research is needed to understand its full effects and treatment potential.
12 citations
,
November 2021 in “The journal of investigative dermatology/Journal of investigative dermatology” Laminin 332 is essential for normal skin cell behavior and structure.
11 citations
,
October 2021 in “Frontiers in Cell and Developmental Biology” Non-coding RNAs are important for hair growth and could lead to new hair loss treatments, but more research is needed.
11 citations
,
February 2019 in “Stem cells international” Skin-derived stem cells grow faster and are easier to obtain than hair follicle stem cells, but both can become various cell types.
9 citations
,
June 2023 in “Cells” Certain natural and synthetic compounds may help treat inflammatory skin diseases by targeting a specific signaling pathway.
8 citations
,
June 2023 in “Journal of clinical medicine” Nanofat shows promise for facial rejuvenation and treating skin issues but needs more research for long-term safety.
6 citations
,
April 2023 in “Biomaterials Research” Special gels help heal diabetic foot sores and reduce the risk of amputation or death.
6 citations
,
December 2022 in “International Journal of Molecular Sciences” Hormone imbalance is linked to Hidradenitis Suppurativa, a skin condition, and treatments like anti-androgenic therapy and metformin can help. It's also suggested to check patients for insulin resistance and Polycystic Ovary Syndrome.