291 citations,
January 2014 in “The Scientific World Journal” Lichen Planus is a less common condition affecting skin and mucous membranes, with various types and associated risk factors, challenging to diagnose, significantly impacts life quality, and may have a risk of cancerous changes in oral lesions.
28 citations,
July 2015 in “American Journal of Clinical Dermatology” People with Lichen Planus, especially with mucosal involvement, are more likely to have Metabolic Syndrome, which increases their risk for heart disease and diabetes.
2 citations,
October 2020 in “International Journal of Dermatology” Lichen planopilaris in men often involves scalp redness and itching, with some also having hair loss, mucosal lichen planus, or thyroid disease, and treatment improved symptoms in nearly half of the cases.
52 citations,
February 2006 in “Archives of Dermatology” Alefacept may effectively treat severe lichen planus, with patients showing significant improvement and no side effects.
155 citations,
June 2009 in “International Journal of Dermatology” Lichen planus is a skin condition that can resolve on its own, is linked to hepatitis C, and increases the risk of skin cancer.
13 citations,
September 2017 in “Skin appendage disorders” Some women with Frontal Fibrosing Alopecia also have Lichen Planopilaris, which can lead to more symptoms and affect hair outside the scalp.
June 2022 in “Journal of the Liaquat University of Medical and Health Sciences” People with lichen planus are more likely to have abnormal blood fats than healthy people.
2 citations,
November 2016 in “PubMed” People with Lichen Planus have thicker carotid artery walls, but it's not solely due to Lichen Planus when other factors are considered.
5 citations,
December 2016 in “Journal of skin and stem cell” People with cutaneous Lichen Planus are more likely to have Metabolic Syndrome and related conditions like high cholesterol, diabetes, and high blood pressure.
April 2021 in “Journal of Investigative Dermatology” Spironolactone safely and effectively treats hair loss in female scarring alopecia patients.
166 citations,
April 2012 in “Journal of The American Academy of Dermatology” Mostly postmenopausal Caucasian women get Frontal Fibrosing Alopecia, which often includes eyebrow loss and has limited treatment success.
66 citations,
February 2013 in “Pediatric Dermatology” Dermoscopy improves diagnosis and treatment monitoring for children's skin infections, inflammations, and hair disorders.
59 citations,
June 2022 in “Frontiers in medicine” There are still challenges in diagnosing and treating chronic skin diseases, but there is hope for future improvements.
32 citations,
December 2018 in “Cytokine” Type I interferons play a key role in the development of various skin diseases.
17 citations,
August 2015 in “Expert Opinion on Pharmacotherapy” The document concludes that oral finasteride and topical minoxidil are effective for genetic hair loss, while other treatments for different types of hair loss show promise but need more research.
11 citations,
April 2020 in “Journal of Dermatological Treatment” Taking oral isotretinoin with creams worked better for treating a type of hair loss than creams alone.
January 2017 in “Springer eBooks” The document explains various skin conditions and their treatments.
September 2023 in “Journal of Cosmetic Dermatology” Finasteride was more effective than hydroxychloroquine in treating frontal fibrosing alopecia.
41 citations,
July 2017 in “Journal of The American Academy of Dermatology” Men with Frontal fibrosing alopecia typically lose hair on the front scalp and sometimes on sideburns and upper lip, with treatments showing varied success.
Higher disease activity in systemic lupus erythematosus is strongly linked to more internal organ damage.
April 2016 in “Journal of the American Academy of Dermatology” Treatment improved some symptoms but not all.
10 citations,
June 2020 in “Journal of Cosmetic Dermatology” Frontal fibrosing alopecia may be linked to genital Lichen sclerosus through an autoimmune process.
2 citations,
December 2003 in “Medical electron microscopy” The skin and mucous membranes can regenerate over the basement membrane after damage, using nearby surviving cells.
1 citations,
January 2024 in “Nature communications” Activating TLR5 in the gut can extend lifespan and improve health in aged mice.
Tjalma Syndrome is a rare condition in people with lupus, causing fluid buildup and high CA-125 levels, but not due to tumors.
Antimalarial agents are effective for LPP, and intralesional steroids are effective for FFA.
89 citations,
February 2002 in “Australasian journal of dermatology” A premenopausal woman had hair loss and skin issues, treated with topical steroids.
47 citations,
June 2014 in “Journal of Dermatological Treatment” Most treatments for lichen planopilaris were found to be generally unsatisfactory.
23 citations,
January 2010 in “Journal of The American Academy of Dermatology” Effective treatments for lichen planopilaris are unclear due to inconsistent results and a lack of strong research evidence.
9 citations,
April 2021 in “Frontiers in Immunology” Unconventional lymphocytes are important for quick immune responses and healing of skin and mucosal barriers.