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Ionizing radiation causes irreversible skin damage, with single doses leading to acute injury and hair graying, and fractional doses causing more severe long-term tissue damage.

A mutation in the Adam10 gene causes freckle-like spots on Hairless mice.

The PP2A-B55α protein is essential for brain and skin development in embryos.

Claudin expression changes help the skin respond to injury.

Adult mice with CBS deficiency show minimal health issues and normal lifespan despite high homocysteine levels.

Keratin genes change gradually during skin cell development and should be used carefully as biomarkers.

Caspase-7 has functions in skin and hair that are not related to cell death.

Krt16-deficient mice help understand skin disorders like PC and FNEPPK.

Newly divided skin cells quickly move to join skin structures due to tissue tension and specific signals.

Certain vitamins and their derivatives can help hair grow longer by activating specific growth signals.

Meis2 is essential for touch sensation and nerve function in mice.

Gene therapy in mice increased lifespan and improved health without causing cancer.

Neutrophils are key in causing chronic itch in atopic dermatitis, and blocking CXCR3 could reduce this itch.

Blocking mTORC1 may help prevent skin cancer by stopping the growth of certain skin stem cells.

Dexamethasone speeds up hair loss in mice, while cyclosporin A slows it down.

Activating Nrf2 in skin cells causes skin disease similar to chloracne in mice.

Steroids stop hair growth temporarily but don't block the signals that start it.

A 3-month stay in space causes skin thinning, disrupts hair growth, and changes muscle-related genes in mice.

Testosterone causes hair loss in AGA mice, which are good for testing baldness treatments, and both minoxidil and cyproterone acetate can prevent this hair loss.

Mice with enhanced regeneration abilities may help develop new regenerative medicine therapies.

BMP signaling is essential for the development of touch domes.

High levels of male hormones in pregnant mice cause heart enlargement and poor heart function in their female babies.

Methionine restriction works better than betaine for treating CBS deficiency symptoms in mice.

The document concludes that certain chemicals can help maintain stem cell pluripotency and that understanding cell states is crucial for tissue regeneration.

Changing the diet of mice lacking the enzyme CBS can affect symptoms related to the genetic condition.

Both human platelet lysate and minoxidil can promote hair growth, but they affect different genes and cell survival rates.

Blue-light activation of TrkA improves hair-follicle stem cells' ability to become neurons and glial cells.

Younger mice's hair-follicle stem cells are better at turning into heart cells than older mice's.

Eyelid cells share signaling components but differ in pathway activity.

BMPR1a-ECD reduces wrinkles much more effectively than retinoic acid.