April 2024 in “Medicina Estética Revista Científica de la Sociedad Española de Medicina Estética (SEME)” This study clarifies the fundamental aspects of intradermotherapy or mesotherapy, tracing its historical development and highlighting its benefits as well as the negative consequences of improper use, specifically addressing its decline due to severe side effects from treatment errors.
December 2023 in “Plants” The researchers investigated the phytochemical content and pharmacological properties of Fissistigma oldhamii and found multiple compounds, primarily in roots and stems, that may contribute to the plant's traditional anti-inflammatory uses in China, including potential antioxidant, anticancer, and antimicrobial effects.
This review highlights the potential of plant-derived natural compounds as biocompatible and biodegradable materials in dermal and transdermal delivery systems, emphasizing their unexplored benefits and detailing recent advances in isolation techniques and drug delivery technologies.
July 2023 in “Drug testing and analysis (Print)” Homemade hair treatments can significantly lower drug levels in hair, possibly causing false-negative drug tests.
February 2023 in “IntechOpen eBooks” This article discusses the various administration methods and considerations for testosterone replacement therapy, highlighting the importance of individualized therapeutic monitoring and potential adverse effects, but reports no new clinical results.
November 2022 in “IntechOpen eBooks” This review discusses nanoparticle-based wound-healing materials, detailing their benefits, limitations, and recent advancements, and emphasizes the need for further understanding to enhance therapeutic outcomes.
May 2016 in “Mayo Clinic proceedings” This case report describes a 26-year-old man whose abdominal pain and other symptoms led to a diagnosis of celiac disease-induced small-bowel intussusceptions, which resolved with a gluten-free diet.
May 2014 in “Nursing Made Incredibly Easy!” This article reviews the challenges and treatment options for pancreatic cancer, emphasizing the need for a collaborative care approach due to the disease's advanced presentation and poor prognosis; it reports no new clinical findings.
July 2013 in “Neurosurgery” This review discusses the use of spinal fMRI to investigate the brainstem and spinal cord and highlights its potential for understanding functional integration, but it reports no new experimental results.
April 2007 in “CRC Press eBooks” This article discusses various vitamin deficiencies and their neurological implications without providing new clinical results; it serves as an informative chapter on nutrient-related neurological conditions.
This abstract lists numerous dermatological side effects and reactions associated with various medications but reports no new research findings.
December 2023 in “Toxicology communications” This report describes a case of prolonged distributive shock attributed to minoxidil overdose, which involved intentional ingestion alongside trauma and NSAIDs, successfully managed with medications and hydration despite persistent low blood pressure.
January 2023 in “IntechOpen eBooks” This chapter reviews various synthetic methods for creating pharmacologically active diazines, particularly focusing on pyrimidines, and discusses their potential in clinical applications. It also examines novel synthetic strategies that improve the drug-like qualities and safety profiles of these compounds.
12 citations
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February 2010 in “Tetrahedron Letters” This article describes the synthesis of novel polyamine-modified minoxidil analogs and conjugates to potentially enhance minoxidil's biological activity, selectivity, and water solubility, but reports no new biological results.
This study reviews the medicinal uses of Catharanthus roseus, highlighting its production of valuable anticancer alkaloids like vincristine and vinblastine, and its applications in treating diabetes, hypertension, and infections, but also notes potential side effects such as nausea and myelosuppression, especially at high doses.
8 citations
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July 1990 in “Archives of Dermatology” This case report details a fixed-drug eruption in a woman linked to the use of dextromethorphan, marking it as a previously unreported skin reaction to this medication.
November 2023 in “Manuju” This paper discusses the complex relationship between polycystic ovary syndrome (PCOS) and hyperprolactinemia, noting a decrease in prolactin levels following bromocriptine treatment, but reports no new clinical findings.
20 citations
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November 2020 in “Stem Cell Research & Therapy” This study found that placenta-derived mesenchymal stem cells overexpressing PRL-1 inhibited adipogenesis in orbital fibroblasts from Graves’ ophthalmopathy patients by modulating specific signaling pathways, suggesting a potential therapeutic strategy.
1 citations
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April 2013 in “The FASEB Journal” In this study, chronic finasteride administration in near-term pregnant rats restored baroreflex control of renal sympathetic nerve activity to levels observed in non-pregnant rats.
November 2023 in “Curēus” This review examines melatonin's role in managing PCOS and its potential to improve hormonal balance, oxidative stress, sleep quality, and mood, but reports no new clinical results.
December 2024 in “Biological and Pharmaceutical Bulletin” In this study, researchers found that minoxidil nanocrystals delivered using MG-MXD@NP, containing methylcellulose and gum arabic, significantly improved hair growth in mice compared to a standard minoxidil lotion, with enhanced delivery to skin tissues and increased markers of hair follicle stem cell activity.
4 citations
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May 2019 in “Journal of Cosmetic Dermatology” This study found that patients experienced less pain when using a 1-mL syringe compared to a 3-mL syringe, despite both having the same needle size.
57 citations
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December 2012 in “Molecules” This study found that mahanimbicine and a crude extract of Murraya koenigii may enhance wound healing in rats by promoting faster wound contraction and higher collagen deposition.
123 citations
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June 2006 in “Journal of Neurobiology” This study reports that progesterone metabolism to DHP and THP is necessary for its neuroprotective effect against kainic acid excitotoxicity in ovariectomized rats, unlike the synthetic progestin MPA.
September 2024 in “Journal of Anatomy and Histopathology” In this study, researchers found that topical application of 3-β-methoxy-Δ18-oleanene (miliacin) in mice sped up the recovery of hair follicles damaged by cyclophosphamide, moving them into a new hair growth cycle more quickly compared to controls.
July 2024 in “Open Repository of the University of Porto (University of Porto)” Dutasteride is more effective than finasteride for hair growth, and pregabalin effectively treats neuropathic pain.
13 citations
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January 2015 in “Molecular Pharmaceutics” This study suggests that minoxidil may serve as a suitable reference drug for high permeability classification in the Biopharmaceutics Classification System due to its consistent permeability across different intestinal segments and pH levels.
137 citations
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December 2006 in “Arthritis Research & Therapy” This study found that mycophenolate mofetil was associated with higher response rates and lower rates of serious side effects, including a lower mortality rate, compared to cyclophosphamide in lupus nephritis treatment.
2 citations
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August 2021 in “Experimental and Therapeutic Medicine” This study suggested that moxibustion treatment before or at the early stage of diminished ovarian reserve in rats may improve ovarian function by modulating androgen balance, though its effects differ across intervention timings.
3 citations
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October 1993 in “Endocrinology” In this study, finasteride inhibited progesterone synthesis in mouse-derived MA-10 Leydig tumor cells by blocking cholesterol side-chain cleavage, but human and rat cells showed minimal sensitivity.