Effect of Syringe Size on Severity of Pain During Local Anesthesia Administration

The study, involving 20 patients undergoing hair restoration surgery, found that the use of a smaller 1-mL syringe resulted in significantly less pain compared to a larger 3-mL syringe when administering local anesthesia injections. Both syringes used a 30-G needle, but the mean pain scores were lower with the 1-mL syringe (2.7 anteriorly and 2.45 posteriorly) than with the 3-mL syringe (4.5 anteriorly and 4.25 posteriorly), with statistical significance (P-values < 0.01). This suggests that smaller syringes should be preferred to minimize pain during injections.