TLDR Miliacin helps damaged hair follicles grow new hair faster.
The study investigated the effects of 3-β-methoxy-Δ18-oleanene (miliacin) on hair follicles in a cyclophosphamide-induced alopecia model using 30 male C57BL/6 mice. The mice were divided into five groups, with the experimental groups receiving topical applications of miliacin or a control solution. Results showed that miliacin accelerated the transition of chemically damaged hair follicles from anagen VI to dystrophic catagen and shortened the telogen phase. This led to the majority of hair follicles in the miliacin-treated group entering a new hair growth cycle, indicating potential benefits for managing chemotherapy-induced alopecia.
38 citations,
September 2017 in “Oncologist” Scalp cooling can help prevent chemotherapy-induced hair loss with a 50-90% success rate and is safe for patients.
30 citations,
July 2017 in “BioEssays” Activating NRF2 might help treat hair disorders by improving antioxidant defenses.
106 citations,
June 2005 in “Journal of Investigative Dermatology” The document concludes that assessing hair follicle damage due to cyclophosphamide in mice involves analyzing structural changes and suggests a scoring system for standardized evaluation.
August 2025 in “Current Issues in Molecular Biology” Periplaneta americana extract helps hair regrowth in mice with alopecia.
August 2024 in “Drug Design Development and Therapy” Decursin shows promise for treating cancer, neuroprotection, inflammation, and hair loss.
21 citations,
November 2021 in “Biomolecules” Eclipta prostrata is a medicinal plant that helps treat diseases, protects the liver and nerves, and promotes hair growth.
205 citations,
September 2018 in “Nutrients” Essential oils from Curcuma species, like turmeric, have compounds that can fight inflammation, cancer, and bacteria, and can also stimulate hair regrowth in bald males.
Vinegar-processed black soybean helps hair growth and prevents hair loss.
