Toxic and Metabolic Disorders of the Nervous System

The 2007 document discussed various toxic and metabolic disorders of the nervous system. It highlighted the effects of vitamin deficiencies and excesses, alcohol-related conditions, and metal intoxication. For instance, Vitamin E deficiency can lead to spinocerebellar syndrome, while excess Vitamin A can cause pseudotumor cerebri. Alcoholism can lead to conditions like beriberi and Wernicke-Korsakoff syndrome. The document also discussed the effects of toxins from various sources and metabolic disorders like nonketotic hyperosmolar state and hepatic encephalopathy. It further detailed the neurological manifestations of renal failure and conditions like central pontine and extrapontine myelinolysis and hypertensive encephalopathy. The severity of these conditions ranged from mild symptoms to severe cases leading to coma or death.