16 citations,
March 2016 in “The journal of investigative dermatology/Journal of investigative dermatology” The Notch signaling pathway helps in mouse hair development through a noncanonical mechanism that does not rely on RBPj or transcription.
12 citations,
August 2016 in “Current opinion in genetics & development” Organs like hair follicles can renew themselves in complex ways, adapting to different needs and environments.
12 citations,
November 2003 in “Journal of the American Academy of Dermatology” Topical diphencyprone helped regrow hair in mice and rats with a condition similar to human hair loss.
6 citations,
May 2021 in “Stem Cell Reviews and Reports” Newly found stem cells in horse hooves show promise for treating a hoof disease called laminitis.
5 citations,
December 2017 in “Tissue and cell/Tissue & cell” Researchers found stem cells in dog hair follicles using specific markers.
2 citations,
January 2018 in “Biology and medicine” High testosterone levels in 20% of the women studied may indicate PCOS, while 80% had low levels with potential health impacts.
1 citations,
August 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” The research created a detailed map of skin cells, showing that certain cells in basal cell carcinoma may come from hair follicles and could help the cancer grow.
1 citations,
April 2019 in “The journal of investigative dermatology/Journal of investigative dermatology” Melanocyte-associated antigens may play a key role in alopecia areata and could be targets for new treatments.
December 2023 in “Journal of the Endocrine Society” Blocking glucocorticoid receptors improves glucose metabolism in a PCOS mouse model.
October 2021 in “Research Square (Research Square)” Hair follicle stem cells in hairpoor mice are disrupted, causing hair loss.
April 2017 in “Journal of Investigative Dermatology” Removing the Crif1 gene in mouse skin disrupts skin balance and hair growth.
September 2016 in “Journal of Dermatological Science” Wnt-10b is important for keeping mouse skin cells healthy for hair growth.
North American ginseng extract helped regrow hair in balding mice.
221 citations,
January 2014 in “Human Reproduction” Adding anti-Müllerian hormone to PCOS criteria lowers the number of women diagnosed.
215 citations,
January 2011 in “Reproductive Biology and Endocrinology” About 7% to 15% of Iranian women have polycystic ovary syndrome, depending on the criteria used to diagnose it.
89 citations,
August 2008 in “Human genetics” The EDAR gene greatly affects hair thickness in Asian populations.
81 citations,
July 2011 in “Lasers in Medical Science” The Lexington LaserComb helped regrow hair in mice with a condition similar to human hair loss.
72 citations,
December 1996 in “Journal of Investigative Dermatology” Human hair follicles can regenerate after removal, but with low success rate.
31 citations,
January 2010 in “GenomeBiology.com (London. Print)” The research concluded that selection significantly shaped the genetic variation of the X chromosome, with certain regions affected by past selective events.
24 citations,
April 2012 in “Developmental Biology” Dermal papillae cells, important for hair growth, come from multiple cell lines and can be formed by skin cells, regardless of their origin or hair cycle phase. These cells rarely divide, but their ability to shape tissue may contribute to their efficiency in inducing hair growth.
14 citations,
December 2017 in “Journal of Bone and Mineral Metabolism” Women with polycystic ovary syndrome have a higher risk of certain fractures.
13 citations,
February 2023 in “Aging” A substance from hair follicle stem cells helps heal skin wounds in diabetic mice by promoting cell growth and preventing cell death.
12 citations,
May 2019 in “Stem cell reviews” Fetal-maternal stem cells in a mother's hair can help with tissue repair and regeneration long after childbirth.
6 citations,
August 2014 in “Toxicologic pathology” Blocking DGAT1 reduces oil gland size in mice and dogs, but only mice experience hair loss.
4 citations,
January 2020 in “Cells” The research found that the gene activity in mouse skin stem cells changes significantly as they age.
2 citations,
August 2023 in “Development” Hair follicles in the back of the rosette fancy mouse have reversed orientations due to a gene mutation.
1 citations,
October 2013 Different ectodermal organs like hair and feathers regenerate differently, with specific stem cells and signals involved in their growth and response to the environment.
May 2024 in “Scientific reports” Twist2 is essential for scarless skin healing and hair growth in mouse fetuses.
March 2024 in “Research Square (Research Square)” Twist2 is essential for proper skin healing and hair growth in developing mice.
Deleting Smad4 and PTEN genes in mice causes rapid, invasive stomach cancer.