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In this study, researchers developed ionizable coenzyme Q10-engineered lipid/fiber microplexes that restored mitochondrial-ribosomal function and enhanced mRNA translation in senescent cells, leading to increased hair follicle density and bone formation in mouse models compared to conventional lipid nanoparticles.

This review discusses the potential of miRNA-mediated hair growth treatments for androgenetic alopecia by targeting DKK1 to modulate the Wnt/β-catenin signaling pathway and reports no new clinical findings.

This study reviewed competing endogenous RNA networks related to skin aging and wound healing, finding mechanisms like UVB-induced senescence and photoaging, as well as potential therapeutic targets for improving skin health and recovery.

This review highlighted the role of microRNAs (miRNAs) in gouty arthritis, emphasizing their potential influence on disease progression through immune and inflammatory regulation, and their prospective use in diagnosis, prognosis, and therapy.

This review discusses various applications of CRISPR-based tools in cancer research, emphasizing their potential for investigating microRNA functions and developing microRNA-based therapies, despite challenges like off-target effects and delivery issues in using CRISPR/Cas9.

This review discusses various potential risk factors and possible therapeutic interventions for polycystic ovary syndrome, including the modulation of gut microbiota, but reports no new findings.

This review discusses various risk factors and potential therapeutic interventions for PCOS but reports no new clinical results.

This study identified distinct plasma miRNA profiles in alopecia areata that may aid in diagnosis and therapy, but further validation is needed to confirm these exploratory findings.

This paper reviews the emerging role of FGF-7 signaling in hair regeneration, highlighting its potential as a target for new therapies despite limited clinical trial data.

This review highlights that microRNAs (miRNAs) play crucial roles in hair follicle development and cycling in cashmere goats, detailing recent advances in understanding their regulatory functions and potential applications in improving cashmere fiber quality and diagnosing hair disorders.

This study found that low-passage exosomes from dermal papilla cells enhance hair follicle stem cell proliferation and that miR-218-5p may serve as a potential biomarker and therapeutic target for hair growth.

This review discusses the role of miRNA/mRNA regulatory networks in skin development, epidermal homeostasis, and tissue remodeling, and suggests potential for miRNA-based therapies in treating skin conditions, but reports no new clinical results.

This study found that patients with androgenetic alopecia exhibit specific miRNA expression profiles, suggesting that abnormal miR-133b expression may inhibit the Wnt/β-catenin pathway and affect hair growth.

This study found that RCS-01 cell therapy for aged skin was well tolerated and associated with increased gene expression related to extracellular matrix homeostasis, suggesting potential skin improvement.

This study found that melatonin implants in cashmere goats significantly altered the expression pattern and co-expression of miRNAs, suggesting a possible role in inducing a second growth of cashmere.

This study examined the genetic basis of alopecia areata by analyzing gene expression differences between patients and healthy controls, identifying critical pathways, hub genes, transcription factors, and miRNAs implicated in the disease, and suggesting potential targets for treatment.

This review discusses the potential of mesenchymal stem/stromal cells and their exosomes in promoting wound healing and skin regeneration, but reports no new experimental results.

This study observed that adding low-level light therapy with the GentleWaves® device to Minoxidil significantly boosted hair regrowth in men with androgenetic alopecia by reducing scalp inflammation.

This study suggests that exosomal miRNAs from human amniotic fluid stem cells may inhibit myofibroblast differentiation and reduce fibrotic scarring in wound healing.

In this study, researchers found that exosomes derived from Pinctada martensii mucus can effectively inhibit melanin production in melanoma cells and zebrafish without adverse effects, potentially offering a promising therapeutic strategy for treating pigmentary disorders by modulating the NF-κB signaling pathway.

This study found that a single 8Gy dose of superficial 50kV X-ray radiation minimizes keloid recurrence after excision, and identified genomic pathways and potential molecular targets for improved keloid therapy.

This study observed distinct plasma miRNA profiles in alopecia areata, identifying several miRNAs downregulated in both mild and severe forms; machine learning models demonstrated strong predictive accuracy, and kinase inhibitors were suggested as promising therapeutic targets based on pathway analysis.

This study found that topically applied liposomal spherical nucleic acids targeting the IL-17 receptor could effectively reduce psoriasis severity in preclinical models.

This research presents a comprehensive workflow for producing EMA-compliant autologous keratinocyte-based therapies for wound healing and explores miRNA-mediated regulations in human keratinocytes and adipose-derived mesenchymal stem cells.

This study suggests that transfection with modified KGF-mRNA enhances keratinocyte reepithelialization in wound therapy by temporarily increasing growth factor expression without affecting nuclear DNA.

This case study describes a rare instance of alopecia universalis in a Japanese patient following an mRNA COVID-19 vaccination.

This case report chronicles a three-year journey of long COVID in a previously healthy 26-year-old, detailing treatment trials and near-total remission, but provides no new generalizable data.

MicroRNAs may help diagnose and treat hair loss disorders.

This article reviews the role of microRNAs in skin-related conditions like psoriasis and wound healing and highlights their potential as therapeutic targets and diagnostic biomarkers, without reporting new experimental results.

In this study, researchers observed that Indian head cactus extract significantly increased the proliferation of human follicle dermal papilla cells and induced the expression of hair growth-related genes, suggesting its potential as a new therapy for promoting hair growth.