Platelet-Rich Plasma Therapy for Telogen Effluvium: A Comprehensive Evaluation of Efficacy and Safety

April 2024

Uzma Dost Muhammad Rajar, Amin Fahim, Sumayya Qazi, Navaid Kazi, Neeta Maheshwary, Arjumand Ahmed-Rph

platelet-rich plasma telogen effluvium Tressfix Serum microRNA hsa-mir-223 hsa-mir-212 PRP

TLDR Combining PRP with Tressfix Serum is more effective for hair regrowth in telogen effluvium than using either alone.

The study investigated the efficacy and safety of combining platelet-rich plasma (PRP) with Tressfix Serum in treating chronic telogen effluvium (TE) in a randomized clinical trial with 60 patients aged 20-40. Participants were divided into three groups: Group A (PRP + Tressfix Serum), Group B (PRP alone), and Group C (Tressfix Serum alone). Group A showed the most significant improvement in hair regrowth and reduction in hair shedding, with a notable decrease in microRNA expression related to TE, particularly hsa-mir-223 and hsa-mir-212. The combination therapy was more effective than individual treatments, suggesting a promising approach for TE. However, the study's small sample size and lack of long-term follow-up indicate the need for further research with larger populations to confirm these findings.

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6 / 77 results

community Do Platelet-rich plasma, PRP work?

in Research/Science 14 upvotes 1 year ago

Someone's brother tried Platelet-rich plasma (PRP) for hair loss; it had minimal effect on hair but improved skin appearance. Microneedling at home was suggested as a more sustainable alternative.

community I have successfully stopped my hormone-induced hair loss ( caused by PCOS,) for 2 years now but I can't seem to be able to regrow the lost hair. Has anyone tried Platelet-Rich Plasma Therapy (PRP)?

in Female 7 upvotes 3 years ago

GentleIris stopped hormone-induced hair loss with diet changes but couldn't regrow lost hair. A reply suggested microneedling instead of Platelet-Rich Plasma Therapy (PRP) for hair regrowth.

community Nice & pure PRP, 3 ml of this is going to the scalp.

in Research/Science 32 upvotes 2 years ago

The use of PRP to treat hair loss and its potential effectiveness when combined with 5 alpha reductase blockers such as Minoxidil or Finasteride.

community Diffuse hair loss and scalp biopsies

in Research 692 upvotes 3 months ago

Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

community Evidenced Based Meta-Analyses and Systemic Reviews of Androgenic Alopecia and Treatments

in Research/Science 15 upvotes 4 years ago

Evidence-based treatments for androgenic alopecia, such as minoxidil, finasteride, low-level laser light therapy, dutasteride, platelet-rich plasma, and topical ketoconazole. It discusses the efficacy, safety, and mechanism of action of these treatments, as well as future developments in understanding this polygenic condition.

community New and Interesting HairLoss Studies/Papers/Reviews

in Treatment 44 upvotes 4 years ago

Hair loss treatments discussed include Dutasteride with Ketoconazole, tissue engineering strategies, and androgenetic alopecia therapies. Massage doubles follicular retention, improving treatment effectiveness.

Related Research

1 / 1 results

research Comparison of the Efficacy of Homologous and Autologous Platelet-Rich Plasma for Treating Androgenic Alopecia

24 citations, November 2017 in “Aesthetic Plastic Surgery”

All types of Platelet-Rich Plasma (PRP) can treat hair loss, but homologous PRP works best due to its higher platelet count and growth factors from multiple donors.