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In this study, researchers found that the microRNA profiles of induced pluripotent stem cells (iPSCs) derived from different adult cell types are largely similar, although each line exhibits some unique gene expression, distinct from both their cells of origin and embryonic stem cells.

Two studies in Cell Stem Cell reported that human and mouse somatic cells can be reprogrammed into induced pluripotent stem cells using microRNAs, eliminating the need for ectopic protein expression.

This review highlights the potential roles of long non-coding RNAs (lncRNAs) in malignant brain tumors, reporting that further research into their involvement in therapy resistance and cancer pathways could improve diagnosis and treatment outcomes.

This review discusses the potential of natural products to induce ferroptosis as a promising therapeutic strategy for non-small cell lung cancer and reports no clinical results; the authors highlight the need for further comprehensive studies.

This review discusses various gene therapy and non-viral delivery methods to promote angiogenesis for chronic wound healing, but it reports no new clinical results.

This study reports that miR-302 promotes pluripotency by inhibiting NR2F2 and indirectly regulating OCT4 in stem cells, enhancing reprogramming efficiency when added to traditional factors.

This study found that induced expression of mir-302 can reprogram human hair follicle cells into induced pluripotent stem cells through a novel epigenetic mechanism involving global demethylation.

OCT4 helps hair stem cells renew and fight aging, potentially aiding hair regrowth.

This review discusses the therapeutic potential of mesenchymal stem cell-derived extracellular vesicles and modern technologies like 3D bioprinting but reports no new clinical results.

This review highlights that incorporating nanomaterials into scaffolds can significantly enhance angiogenesis in tissue regeneration by simulating extracellular matrix structures and effectively delivering angiogenesis-related factors, offering promising designs for vascularization and therapeutic applications.

This study found that increasing the levels of specific microRNAs from the miR-17∼92 cluster improved wound healing in mice by reducing inflammation, suggesting a potential therapeutic approach for chronic wounds.

Dermal exosomes with miR-218-5p boost hair growth by controlling β-catenin signaling.

In this study, miR-218-5p was found to enhance hair shaft growth and positively regulate the Wnt signaling pathway by targeting SFRP2 during skin and hair follicle development.

In this study, researchers observed that hyperandrogenic PCOS patients exhibited distinct miRNA and TGFβ signaling gene expression patterns in granulosa cells, suggesting these factors may play a role in PCOS pathogenesis.

This study found that the microRNA miR-22 is a key regulator of the hair cycle, influencing hair loss by promoting the transition from growth to rest phases and repressing keratinocyte differentiation.

This study identified key genes and miRNAs involved in feather morphogenesis in Zhedong White geese, highlighting a negative correlation between FOXO3 and miR-144-y.

This study reports that miR-22 promotes cancer progression and metastasis by maintaining Wnt/β-catenin signaling and cancer stem cell function.

In this study, exosome-mimetic nanovesicles derived from neural progenitor cells promoted hair follicle regeneration in mice by activating the Wnt/β-catenin signaling pathway.

In this study, hair shaft miR-29a levels were significantly lower in scleroderma patients than in controls, suggesting that hair microRNAs could serve as independent biomarkers for the disease.

This study found that lncRNA H19 may regulate CTGF expression in KGN cells by acting as a "sponge" for miR-19b, potentially influencing polycystic ovary syndrome development.

This study found that miR-150 enhances the resolution ability of endothelial progenitor cells in venous thrombosis by promoting cell differentiation and proliferation through specific gene regulation pathways.

This study suggests that miRNAs, particularly miR-195-5p, may regulate the loss of hair follicle inductivity in cultured dermal papilla cells by suppressing the Wnt/β-catenin pathway.

This study found that extracellular vesicles from low-passage dermal papilla cells may activate hair growth by delivering miR-140-5p, which downregulates BMP2 signaling, suggesting potential therapeutic targets for alopecia.

The researchers reported that exosomes from hypoxic M2 macrophages, enriched with miR-26b-5p, promoted proliferation, migration, and invasion in human keloid fibroblasts through the PTEN-PI3K/AKT pathway, highlighting miR-26b-5p's role in keloid development.

In this study, researchers found that unexplained liver damage in PCOS patients may involve iron metabolism and the miR-761-hepcidin/GPX4 axis, suggesting potential therapeutic targets.

This study found that upregulating miR-325-3p in glioma suppresses tumor cell proliferation, migration, and invasion by inhibiting FOXM1, suggesting its potential as a treatment target for brain cancer.

This study found that circRNA-1926 promotes hair follicle stem cell differentiation in cashmere goats by sponging miR-148a/b-3p to increase CDK19 expression.

In this study, researchers found that miR-3606-3p is significantly downregulated in skin fibrosis and correlates with disease severity, with its ability to inhibit key signaling pathways suggesting potential therapeutic applications for conditions like systemic sclerosis and keloids.

This study demonstrated that a device combining hyaluronic acid-based dissolving microneedles and lipid polymer hybrid nanoparticles effectively delivered miR-218 to promote hair growth in a shaved mouse model, outperforming topical smear treatment without safety concerns.

This study found that knockdown of PCAT1 inhibited hair follicle regeneration in nude mice by disrupting the miR-329/Wnt10b axis and Wnt/β-catenin signaling, highlighting PCAT1's role in promoting follicle regrowth.