September 2024 in “Actas Dermo-Sifiliográficas” Sublingual minoxidil is a safe and effective treatment for hair loss, especially in women.
July 2013 in “Our Dermatology Online” Minoxidil 2% is more effective than tacrolimus 0.1% for hair regrowth in mild to moderate patchy hair loss, and combining both might give better results.
90 citations,
May 1972 in “Clinical Pharmacology & Therapeutics” Minoxidil quickly leaves blood, turns into urine metabolites, and has lasting blood pressure-lowering effects.
35 citations,
July 1981 in “Clinical Pharmacology & Therapeutics” Minoxidil can cause dangerous fluid buildup around the heart.
35 citations,
December 1979 in “Naunyn-schmiedebergs Archives of Pharmacology” These drugs raise prostaglandin-like material in dog blood, possibly causing blood vessel widening.
34 citations,
October 1994 in “Journal of Pharmaceutical Sciences” Ethanol over 50% helps minoxidil absorb better into skin.
34 citations,
January 1989 in “Toxicologic Pathology” A study found that minoxidil can damage the hearts of dogs and pigs, cautioning its use in humans.
33 citations,
June 1995 in “Journal of Pharmaceutical Sciences” More ethanol increases minoxidil delivery, but too much lowers efficiency.
31 citations,
October 2002 in “Dermatologic Surgery” Minoxidil helps stabilize hair loss, increase density, and reduce shedding after hair transplant surgery.
30 citations,
April 1990 in “Clinical Pharmacology & Therapeutics” Tretinoin cream boosts minoxidil absorption, possibly improving hair loss treatment.
28 citations,
March 2017 in “Scientific Reports” Minoxidil may protect nerves and improve hair quality during paclitaxel treatment.
25 citations,
January 1983 in “Analyst” Method measures minoxidil in tablets accurately and easily.
23 citations,
October 2006 in “Journal of Dermatological Science” Ethosomal minoxidil improves hair growth by penetrating deeper into skin and shortening hair cycle.
20 citations,
March 2019 in “Journal of The European Academy of Dermatology and Venereology” Minoxidil effectively and safely treats patchy hair loss, but more research needed.
20 citations,
January 1994 in “Archives of Biochemistry and Biophysics” Minoxidil needs specific structure to block lysyl hydroxylase; exploring alternatives may keep benefits without this effect.
15 citations,
November 2017 in “Drug Delivery and Translational Research” Certain extracts from Curcuma aeruginosa Roxb. and germacrone can boost the skin's absorption of minoxidil, a hair growth promoter, making it more effective.
14 citations,
August 2019 in “Journal of Dermatological Treatment” 10% minoxidil solution better promotes hair growth and reduces hair loss without significant side effects.
7 citations,
February 2019 in “Journal of Molecular Liquids” Minoxidil dissolves better in propylene glycol and water as temperature and propylene glycol amount increase.
5 citations,
April 2022 in “Pharmaceutics” Minoxidil nanoparticles significantly boost hair growth in mice compared to regular minoxidil.
5 citations,
March 2016 in “Medical journal, Armed Forces India” A man experienced life-threatening shock after swallowing hair growth solution.
4 citations,
July 2022 in “Clinical and Experimental Dermatology” Using more than 5% minoxidil can help hair growth more, but results vary and side effects may increase.
3 citations,
October 2014 in “Pharmaceutical Development and Technology” The study found a way to improve a skin-applied minoxidil formula using a specific design method.
December 2024 in “Journal of Cosmetic Dermatology” Oral minoxidil rarely causes pericardial effusion, especially at low doses.
June 2024 in “Dermatology and therapy” Low-dose oral minoxidil is safe for treating children's hair disorders.
April 2024 in “AAPS PharmSciTech” New microneedle method improves hair regrowth treatment delivery.
March 2024 in “JAAD International” Using both topical and oral minoxidil doesn't significantly reduce temporary hair shedding.
February 2024 in “Actas Dermo-Sifiliográficas” Dermatologists recommend oral dutasteride for male hair loss, low-dose oral minoxidil for female hair loss, and a multidisciplinary approach for young patients, with caution during pregnancy.
September 2022 in “Journal of pharmaceutical sciences” Thicker minoxidil solutions work better and need less frequent application.
January 2012 in “The Year book of dermatology” Many treatments for alopecia areata have inconsistent results; for under 10s, use minoxidil with a corticosteroid, and for over 10s, add ILC and consider diphenylcyclopropenone for widespread cases.
February 2023 in “Journal of The American Academy of Dermatology” Low-dose oral minoxidil helps increase hair density in traction alopecia.