The Role of Patient and Drug-Related Factors in Oral Minoxidil and Pericardial Effusion: Analyses of Data From the United States Food and Drug Administration Adverse Event Reporting System

    December 2024 in “ Journal of Cosmetic Dermatology ”
    Aditya K. Gupta, Mary A. Bamimore, Robert S. Haber … Mesbah Talukder
    Studysummary This study found that oral minoxidil was more likely to be associated with pericardial effusion compared to other adverse effects, with the relationship appearing dose independent.
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    Research cited in this study 13

    1. Efficacy and Safety of Oral Minoxidil Versus Topical Solution in Androgenetic Alopecia: A Meta-Analysis of Randomized Clinical Trials International Journal of Dermatology · 2024
    2. Evaluation of Pericardial Effusions in Alopecia Patients on Low-Dose Oral Minoxidil Therapy Journal of Drugs in Dermatology · 2024
    3. Minoxidil-Induced Pleuro-Pericardial Effusion With Tamponade Curēus · 2023
    4. Low Dose Oral Minoxidil and the Conundrum of Cardiovascular Complications Dermatology online journal · 2023
    5. Pericardial, Pleural Effusion and Anasarca: A Rare Complication of Low-Dose Oral Minoxidil for Hair Loss JAAD case reports · 2022
    6. Safety of Low-Dose Oral Minoxidil for Hair Loss: A Multicenter Study of 1404 Patients Journal of The American Academy of Dermatology · 2021
    7. Coming Full Circle (Almost): Low Dose Oral Minoxidil for Alopecia Journal of The American Academy of Dermatology · 2021
    8. Safety of Low-Dose Oral Minoxidil Treatment for Hair Loss: A Systematic Review and Pooled Analysis of Individual Patient Data Dermatologic Therapy · 2020
    9. Oral Minoxidil Improves Background Hair Thickness in Lichen Planopilaris Journal of The American Academy of Dermatology · 2020
    10. Minoxidil And Its Use In Hair Disorders: A Review Drug Design Development and Therapy · 2019
    11. Case Series of Oral Minoxidil for Androgenetic and Traction Alopecia: Tolerability and the Five C’s of Oral Therapy Dermatologic Therapy · 2018
    12. Minoxidil and Pericardial Effusion: An Idiosyncratic Reaction Clinical Pharmacology & Therapeutics · 1981
    13. Long-Term Treatment of Severe Hypertension with Minoxidil, Propranolol, and Furosemide Circulation · 1975

    Related research 2

    1. Minoxidil Sulfotransferase Enzymatical Activity in Plants: A Novel Paradigm in Increasing Minoxidil Response in Androgenetic Alopecia Journal of Cosmetic Dermatology · 2023
    2. Compliance to Topical Minoxidil and Reasons for Discontinuation Among Patients With Androgenetic Alopecia Dermatology and therapy · 2023