January 2025 in “SSRN Electronic Journal” This study developed a bioinspired hydrogel (BD@HH6) that exhibited strong antimicrobial and antioxidant properties, accelerated wound healing in mice by promoting angiogenesis and reducing inflammation, and represents a potential new approach for managing chronic wound infections without relying on antibiotics.
2 citations
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September 2020 in “Hair transplant forum international” This study reports that a new multi-slit knife for hair transplant procedures reduces surgical time and increases precision by enabling quick creation of equidistant "brick-pattern" sagittal slits.
14 citations
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June 2016 in “Biomaterials” This study observed that MAA beads improved vascularization in non-diabetic male mice by modulating the Shh signaling pathway in wound granulation tissue, but showed no such effects in females.
July 2025 in “Journal of Investigative Dermatology” Wnt signaling helps regenerate hair follicles in wounds by reducing skin cell sensitivity to mechanical stress.
July 2026 in “Methods and Protocols” In this study, researchers developed a mouse model of non-healing wounds associated with streptozotocin-induced diabetes and found that it significantly delayed regenerative processes compared to healthy controls, suggesting its relevance for preclinical testing of wound regeneration drugs.
27 citations
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March 2006 in “Dermatologic surgery” This review discusses the widespread acceptance of micropigmentation for cosmetic purposes and its various medical applications, but reports no new clinical findings.
August 2025 in “OPAL (Open@LaTrobe) (La Trobe University)” This preclinical study found that a machine-learning-driven strategy for fabricating microneedles with optimal hardness and rapid dissolution significantly promoted hair regrowth in androgenetic alopecia mice by activating the Wnt/β-catenin pathway, surpassing the effects of minoxidil.
733 citations
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September 2009 in “Journal of Cell Science” This article reviews the complex process of wound repair, emphasizing recent microarray studies and proteomic analyses, but reports no new clinical results.
7 citations
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June 2025 in “Nano Energy” This study reports that triboelectro-responsive DNA hydrogels, enhanced with conductive polymers and triboelectric stimulation, effectively accelerate wound healing and exhibit strong anti-bacterial and anti-inflammatory properties, achieving 99.8% closure of bacterium-infected diabetic wounds in 14 days.
This study provides a detailed analysis of cell subpopulations in a mouse model of wound-induced hair follicle regeneration, revealing specific cellular dynamics and heterogeneity that may influence hair follicle neogenesis.
17 citations
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May 2015 in “Aesthetic Plastic Surgery” FUE hair transplantation using a micromotor is effective and gives natural results with few complications.
2 citations
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April 2024 in “Biotechnology Progress” This study designed a micromold template for creating controlled-sized, multicellular tumor spheroids, finding that HEK-293 cells formed consistent spheroids with high circularity and viability after 7 days, influenced by cell seeding density and treatment conditions.
March 2026 in “Materials Today Bio” This study developed a minimally invasive cryo-microneedles array patch (cryo-MAP) technique for transplanting hair follicle organoids, showing successful hair growth and complex skin structure regeneration with over 86% success in 15 days, opening new possibilities in tissue engineering.
21 citations
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January 2018 in “Journal of Investigative Dermatology” This study found that large excisional wounds in rats across seven strains do not regenerate new hair follicles, unlike in mice, possibly due to differences in epidermal competence and transcriptional profiles.
April 2025 in “OPAL (Open@LaTrobe) (La Trobe University)” This study developed a dissolvable microneedle system loaded with nanozymes and minoxidil that enhanced hair regeneration in androgenetic alopecia mouse models by improving blood flow, reducing reactive oxygen species, and increasing cell proliferation compared to minoxidil alone.
January 2026 in “SSRN Electronic Journal” January 2026 in “SSRN Electronic Journal” January 2026 in “SSRN Electronic Journal” 319 citations
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March 2023 in “Science Advances” This study demonstrated that a wearable bioelectronic patch with combined therapy significantly accelerated chronic wound healing in a rodent model by monitoring and treating wounds noninvasively.
10 citations
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May 2020 in “Journal of Dermatological Treatment” This study found that combining microneedling with 5% minoxidil improved hair growth in Chinese men with androgenetic alopecia, possibly through activating the Wnt/β-catenin signaling pathway.
39 citations
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April 1992 in “Development” In this study, researchers detailed how hair follicles regenerate after microsurgical amputation, observing a wound reaction involving dynamic dermal-epidermal interactions and changes in extracellular matrix components.
1 citations
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June 2006 in “Journal of Cosmetic Dermatology” This study found that photoepilation in mice may disrupt normal dermal wound healing and increase the risk of hypertrophic scars or keloids.
36 citations
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November 2011 in “Journal of the European Academy of Dermatology and Venereology” This study identified distinct microscopic characteristics of acne scars, including inflammatory infiltrates and insufficient collagen deposition, suggesting that treatment should consider these histopathological findings and employ combination therapy.
January 1974 in “Almogaren” This study developed a microdroplet technology to produce cell microspheres that successfully induced hair follicle regeneration in a mouse model, suggesting potential improvements in hair loss treatments.
July 2026 in “Materials Today Bio” This study developed a novel hydrogel that improved healing in diabetic infected wounds on mobile sites by controlling infection, inflammation, and mechanical stress, promoting skin regeneration without excess scarring.
July 1998 in “Dermatologic Surgery” Various techniques and tools for hair restoration were presented in 1998, including a mathematical model for donor area, use of lasers in surgery, methods for controlling grafted hair direction, and ways to increase graft yield. Satisfaction rates were around 39%, and studies showed trauma and dehydration can damage hair follicles.
83 citations
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September 2021 in “Advanced functional materials” This study introduced a multifunctional DNA hydrogel dressing that may enhance wound healing by promoting tissue regeneration, nerve repair, and immune response in diabetic infectious wounds.
Since 1995, we only use Follicular Unit Transplantation for hair restoration and stopped using minigrafting/micrografting techniques.
51 citations
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March 2018 in “Journal of Investigative Dermatology” This study highlights the need for standardized preclinical murine models to improve the translation of wound healing research to human clinical applications, specifically noting variations in diabetes duration, animal sex, and assessment methods on healing outcomes in rat models.
12 citations
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April 2025 in “Discover Pharmaceutical Sciences” This review examines microneedle patches for drug delivery, detailing their designs, materials, manufacturing methods, and potential advantages, but reports no new clinical results.