Non-Healing Wound Model in Diabetic C57BL/6 Mice

    July 2026 in “ Methods and Protocols ”
    L. A. Rzhanova, Ekaterina V. Kuzmenko, Alena A. Permyakova … Elena I. Morgun
    Studysummary In this study, researchers developed a mouse model of non-healing wounds associated with streptozotocin-induced diabetes and found that it significantly delayed regenerative processes compared to healthy controls, suggesting its relevance for preclinical testing of wound regeneration drugs.
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    Research cited in this study 2

    1. The Model of an Ischemic Non-Healing Wound: Regeneration After Transplantation of a Living Skin Equivalent Sovremennye tehnologii v medicine · 2023
    2. Symmetry Breaking of Tissue Mechanics in Wound-Induced Hair Follicle Regeneration of Laboratory and Spiny Mice Nature Communications · 2021