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The researchers developed semi-dissolving microneedle patches using TEMPO-oxidized bacterial cellulose nanofibers, which allow effective transdermal drug delivery by forming micro-channels for large drug quantities, overcoming traditional microneedles' low drug loading.

This study found that adipose-derived mesenchymal stromal cell secretome, particularly when preconditioned with IFNγ, significantly influences cell motility and anti-inflammatory responses, enhancing its potential as a regenerative therapy.

This study suggests that epithelial-derived pop-up keratinocytes (ePUKs) may improve regenerative medicine applications due to their specific phenotype and increased expression of proteins involved in regulating cellular movement and wound healing.

In this study, researchers conducted single-cell RNA sequencing to reveal that proinflammatory fibroblasts and vascular endothelial cells play significant roles in the immune microenvironment of keloids, suggesting potential targets for new therapeutic approaches.

This study evaluated nanovesicles derived from Polygonum multiflorum roots, finding that they promote dermal papilla cell proliferation and activate β-catenin signaling, which in turn enhances hair shaft elongation in ex vivo cultured human hair follicles, suggesting their potential use for alopecia treatment.

This review explores how exosomes can be used therapeutically in autoimmune skin diseases, emphasizing that their properties like stability and biocompatibility make them promising for targeting immune signaling pathways involved in conditions such as inflammation and scleroderma.

This review examines mesotherapy for local fat reduction, detailing its mechanisms, safety concerns, and the need for research toward FDA-approved uses, but reports no new clinical findings.

This study introduced a novel in vitro assay for tracking melanosome transfer between melanocytes and keratinocytes, facilitating the quantification of melanin transfer and supporting the role of filopodia as a conduit.

In this study, niosomal formulations enhanced minoxidil skin accumulation compared to commercial and control solutions, suggesting a potential improvement for topical delivery in hair loss treatment.

This study found that skin surface lipids contain measurable mRNAs, providing a non-invasive way to study skin diseases, with specific gene expression changes observed in atopic dermatitis patients.

This study examined the expression of fatty acid transporters and binding proteins in mouse sebaceous glands and found that CD36 did not affect the localization of other related molecules.

This study found that hMSC secretomes from umbilical cord Wharton's jelly had the most potent angiogenic effects, whereas those from adipose tissue demonstrated the weakest angiogenic potential.

This review examines the promising role of nanocarriers, specifically liposomes and ethosomes, in enhancing transdermal drug delivery for skin diseases. Ethosomes, highlighted for their ability to penetrate deeper skin layers, show potential for more effective treatments but require further clinical investigation.

This review discusses ethosomes as potential carriers for delivering drugs into deeper skin layers and provides no new clinical results, suggesting a need for further studies on their efficiency in dermal therapies.

This study developed and tested a novel microneedle treatment loaded with nanoparticles for vitiligo, leading to enhanced skin repigmentation by targeting immune cells and reducing oxidative stress in a minimally invasive manner.

This study found that exosomes derived from human bone marrow mesenchymal stem cells significantly promote cutaneous wound healing in rats by modulating the TGF-β/Smad signaling pathway.

In this review, the authors discuss the promising role of exosomes from various cell sources as potential cell-free therapies for diabetic foot ulcers, highlighting their therapeutic benefits in wound healing and the challenges faced in their clinical application.

This study found that cholesterol- and phospholipid-free multilamellar niosomes improved skin deposition and targeted deeper hair follicles better than hydrophobic PLGA nanoparticles for transdermal drug delivery.

This systematic review found that mixed epithelial and stromal tumor of the seminal vesicle (MESTSV) is characterized by abundant stromal proliferation, architectural heterogeneity, and strong immunoreactivity for ER/PR, with most being benign but warranting surveillance for possible recurrence or metastasis.

This study found that thymosin β4 is highly expressed in multiple human tissues and may play a role in organ function and angiogenesis through co-localization with VEGF.

This study introduced a bioengineered model that simulates acne's microenvironment in mice, enabling the exploration of host and P. acnes interactions and presenting a novel platform for anti-acne drug and vaccine screening.

In this study, hUCMSCs-Exo significantly accelerated wound healing in rat perianal fistulas with notable safety, potentially through the activation of the HIF-1α/TGF-β/Smad signaling pathway.

This article reviews the role of liposomes in dermatology and does not report new clinical results.

This study found that gentamicin-loaded exosomes derived from bovine leukocyte spleen extract enhanced antimicrobial activity and promoted tissue regeneration in infected diabetic mouse wounds, suggesting a potential innovative therapeutic strategy for diabetic foot ulcers by combining infection control with pro-regenerative and immunomodulatory effects.

This study found that two microRNAs, oar-miR-23b and oar-miR-133, inhibit the development of hair follicles in superfine wool sheep by targeting genes involved in key signaling pathways, suggesting their potential use as molecular markers for breeding fine wool sheep.

This study found that PPD-Lip@RES may effectively promote hair growth in models of telogen effluvium and androgenetic alopecia, suggesting its potential as a promising treatment strategy by addressing the underlying pathological and physiological processes of hair loss.

In this chapter, researchers discuss how microRNAs (miRNAs) interact with vitamin D signaling, highlighting their emerging role as mediators in vitamin D-regulated disorders and their potential for developing miRNA-based clinical applications.