research Self-Amplifying RNA Approach for Protein Replacement Therapy
Self-amplifying RNA could be a better option for protein replacement therapy with lower doses and lasting effects, but delivering it into cells is still challenging.
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research Resting No More: Redefining Telogen, the Maintenance Stage of the Hair Growth Cycle
The telogen phase of hair growth is active and important for preparing hair follicles for regeneration, not just a resting stage.
research Life Sciences Discovery And Technology Highlights
New technologies show promise in healing wounds, treating cancer, autoimmune diseases, and genetic disorders.
research Up-Regulation of Androgen Receptor by Heat Shock Protein 27 and miR-1 Induces Pathogenesis of Androgenic Alopecia
Higher levels of heat shock protein 27 and lower levels of miR-1 can increase AR levels, leading to hair loss in men.
research TRP Channels in Skin Biology and Pathophysiology
TRP channels in the skin are important for sensation and health, and targeting them could help treat skin disorders.
research Induced Pluripotent Stem Cells From Human Hair Follicle Keratinocytes As A Potential Source For In Vitro Hair Follicle Cloning
Human hair follicles can be used to create stem cells that might help clone hair for treating hair loss or helping burn patients.
research Male-Pattern Baldness, Common Latent Viruses, and Microcompetition
Common latent viruses might contribute to male-pattern baldness by disrupting cell processes that normally suppress hair loss-related proteins.
research Macrophage-Derived Extracellular Vesicle Promotes Hair Growth
Special cell particles from macrophages can help hair grow.
research Matrix Metalloproteinase-9 Is Involved in the Regulation of Hair Canal Formation
MMP-9 is essential for proper hair canal formation.
research Hair Follicle Morphogenesis and Epidermal Homeostasis in We/We Wal/Wal Mice with Postnatal Alopecia
The we/we wal/wal mice have defects in hair growth and skin layer formation, causing hair loss, useful for understanding alopecia.
research Suppression of Cutibacterium Acnes-Mediated Inflammatory Reactions by Fibroblast Growth Factor 21 in Skin
FGF21 can help reduce skin inflammation caused by C. acnes.
research The Role of hsa-miR-193a-5p as an Important Factor for Control of Inositol in Alopecia Areata
hsa-miR-193a-5p may help diagnose and treat alopecia areata.
research Improvement of Androgenic Alopecia by Extracellular Vesicles Secreted from Hyaluronic Acid-Stimulated Induced Mesenchymal Stem Cells
HA-stimulated stem cell vesicles improved hair growth in male mice with androgenetic alopecia.
research Emerging Roles of Sox6 in the Renal and Cardiovascular Systems
Sox6 is important in heart and kidney health, affecting diseases like diabetes, heart disease, and high blood pressure.
research Hairless Plays a Role in Formation of Inner Root Sheath via Regulation of Dlx3 Gene
Hairless protein affects hair follicle structure by regulating the Dlx3 gene.
research Hair Loss and Telogen Effluvium Related to COVID-19: The Potential Implication of Adipose-Derived Mesenchymal Stem Cells and Platelet-Rich Plasma as Regenerative Strategies
COVID-19 can cause hair loss, and treatments like PRP and stem cells might help.
research Patient and Device Generated Variability in Platelet-Derived Growth Factors During Platelet-Rich Plasma Therapy for Hair Loss
Differences in growth factors in platelet-rich plasma therapy for hair loss can vary between patients and can be influenced by the devices used, possibly leading to inconsistent results.
research Epidermal Development in Mammals: Key Regulators, Signals from Beneath, and Stem Cells
Skin development in mammals is controlled by key proteins and signals from underlying cells, involving stem cells for maintenance and repair.
research Basic Concepts, Current Evidence, And Future Potential For Gene Therapy In Managing Cutaneous Wounds
Gene therapy shows promise for improving wound healing, but more research is needed for human use.
research Induced Pluripotent Stem Cells from Human Hair Follicle Keratinocytes as a Potential Source for In Vitro Hair Follicle Cloning
Human hair follicle cells can be turned into stem cells that may help clone hair for treating hair loss or burns.
research Identifying Molecular Targets for Reverse Aging Using Integrated Network Analysis of Transcriptomic and Epigenomic Changes During Aging
Curcumin may help reverse aging by targeting specific genes.
research Novel Insights Into the Molecular Mechanisms Underlying Generalized Glucocorticoid Resistance and Hypersensitivity Syndromes
Genetic defects in the glucocorticoid receptor gene can cause conditions with abnormal sensitivity to stress hormones, and other factors may also affect this sensitivity.
research Polycystic Ovary Syndrome (PCOS) – An Overview
PCOS is a hormonal disorder causing symptoms like irregular periods and acne, and increases the risk of diabetes and heart disease.
research Problems and Solutions for Platelet-Rich Plasma in Facial Rejuvenation: A Systematic Review
PRP shows promise for improving facial wrinkles, skin elasticity, and hair growth, but more research is needed to standardize its use and understand its effects.
research Polycystic Ovary Syndrome (PCOS): An Inflammatory, Systemic, Lifestyle Endocrinopathy
PCOS is a complex condition in women that can lead to health issues, and lifestyle changes are the best management approach.
research Effects of Natural Products on Skin Inflammation Caused by Abnormal Hormones Secreted by the Adrenal Gland
Natural products may help treat skin inflammation from abnormal adrenal hormones.
research Human Hair Follicle-Derived Mesenchymal Stem Cells Promote Tendon Repair in a Rabbit Achilles Tendinopathy Model
Human hair follicle stem cells help repair tendon injuries.
research Reductive Stress Selectively Disrupts Collagen Homeostasis and Modifies Growth Factor-independent Signaling Through the MAPK/Akt Pathway in Human Dermal Fibroblasts
Reductive stress messes up collagen balance and alters cell signaling in human skin cells, which could help treat certain skin diseases.
research Heme Oxygenase and the Skin in Health and Disease
HO-1 helps skin health and healing but can worsen melanoma; it's a potential treatment target for skin diseases.
research The Role of ADAM17 in PCOS Pathogenesis: A Review Paper
ADAM17 could be a potential target for treating PCOS.