The Role of hsa-miR-193a-5p as an Important Factor for Control of Inositol in Alopecia Areata

The study identifies hsa-miR-193a-5p as significantly over-expressed in alopecia areata (AA) patients compared to healthy controls, suggesting its role in AA's onset or progression. With a sample size of 77 AA patients and 75 controls, the study found that hsa-miR-193a-5p impacts the IPPK gene, which is involved in the inositol phosphorylation and Phosphatidylinositol signaling pathways, crucial for hair growth. The findings highlight hsa-miR-193a-5p as a potential diagnostic and therapeutic target for AA, with future research needed to validate these results with larger sample sizes and lesional skin biopsies.