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research Minoxidil
research ORAL MINOXIDIL EFFICACY AND SAFETY IN MALE ANDROGENETIC ALOPECIA - A LITERATURE REVIEW
This review concluded that low-dose oral minoxidil is an effective and well-tolerated treatment for male androgenetic alopecia, with significant hair density improvements and manageable side effects.
research 경옥고가미방 추출물이 생쥐의 양모 및 발모 관련 단백 발현에 미치는 영향
In this study, Gyungohkgo-gamibang extract significantly stimulated hair growth and increased hair density and thickness in an alopecia model of C57BL/6 mice, indicating its potential as a hair growth tonic.
research STABILITY INDICATING AN LC-ESI-MS/MS METHOD FOR THE QUANTIFICATION OF MINOXIDIL IN PHARMACEUTICAL DOSAGE FORMS
This study developed a novel LC-ESI-MS/MS method to quantify Minoxidil in pharmaceutical forms, finding it precise, accurate, and robust. It withstands excipient and degradant interference, although Minoxidil degrades under some stress conditions but remains stable thermally.
research The effect of Gyungokgo-gamibang extract on hair growth and protein expression in mice
This study found that Gyungohkgo-gamibang extract and minoxidil both significantly stimulated hair growth and increased hair density and thickness in C57BL/6 mice compared to a vehicle treatment.
research Pediatric Minoxidil Exposures Reported to Texas Poison Centers
This study suggests that most pediatric minoxidil exposures reported to Texas poison centers were unintentional, typically non-serious, and often manageable at home, despite concerns about serious adverse effects.
research Hyaluronic acid microneedles enhance transdermal delivery of minoxidil derivatives with 1,2,4-oxadiazole-5-one unit for effective hair regeneration: Insights from X-ray crystallography and animal models
Hyaluronic acid microneedles help deliver minoxidil derivatives effectively for hair regrowth.
research Biodegradable composite from discarded hair keratin and graphene oxide with improved mechanical, thermal and barrier properties: an eco‐friendly solution to waste materials
This study found that integrating graphene oxide into a biodegradable composite made from discarded hair keratin enhanced its structural properties, biodegradability, and gas barrier performance, indicating potential use as an eco-friendly packaging material.
research Demonstration of photochemical grid model usage for ozone control assessment
This case study reports that ingestion of topical minoxidil, used for hair loss, can cause severe circulatory shock and acute pulmonary edema, necessitating immediate medical intervention with fluids and vasopressors.
research Effects of Skin Environmental Changes by Steam Towel, Ethanol, l-Menthol and Carpronium on the Drug Behavior in the Minoxidil Nanoparticles-applied Mice
In this study, pre-treatment with steam towel, l-menthol, and CA-carpronium enhanced the absorption of minoxidil nanoparticles in mice, potentially increasing therapeutic efficiency without side effects.
research Electrochemical Detector for Liquid Chromatography: Determining Minoxidil in Hair-Growth Pharmaceuticals
This study observed that carbon paste electrodes catalyze the electrooxidation of minoxidil more efficiently than other electrode types, with a detection limit of approximately 20 ng mL^-1.
research Magnetic coiffure: Engineering of human hair surfaces with polyelectrolyte-stabilised magnetite nanoparticles
This study demonstrated that human hair can be coated with Fe3O4 nanoparticles, allowing it to be oriented and moved by a magnetic field, which may enhance drug delivery and hair care applications.
research Minoxidil Nano-hydrogel Based on Chitosan and Hyaluronic Acid for Potential Treatment of Androgenic Alopecia
The new minoxidil hydrogel improves delivery and is safe for treating hair loss.
research Design and Evaluation of Hydrogel-Thickened Microemulsion for Topical Delivery of Minoxidil
This study found that microemulsion and microemulsion-based hydrogels may offer a more effective and sustained topical delivery method for minoxidil compared to conventional solutions for hair loss treatment.
research Efficacy and safety of low-dose oral minoxidil in the management of androgenetic alopecia
This source suggests that oral minoxidil could be a safe and effective treatment option for both female and male androgenetic alopecia, although it is currently used off-label.
research Iontophoresis of minoxidil sulfate from hydrophilic gels for the topical treatment of androgenic alopecia
Minoxidil sulfate gel can be used to treat hair loss.
research Hair Manganese as a Marker of Cardiometabolic Status Rather than Coronary Artery Disease Severity—An Exploratory Pilot Study
This study found that hair manganese levels did not vary by acute coronary syndrome or stable coronary artery disease severity, but a modest, non-significant correlation with body mass index suggests a potential link between manganese homeostasis and cardiometabolic status that warrants further investigation.
research Radioimmunoassay of Minoxidil in Human Serum
This study developed a specific radioimmunoassay to measure minoxidil levels in human serum directly from a single oral dose.
research Minoxidil oral en alopecia androgénica: estudio retrospectivo acerca de su seguridad en práctica clínica real
In this descriptive retrospective study, researchers reported that low-dose oral minoxidil (0.25-5mg/day) for androgenic alopecia demonstrated a good safety profile, with 84.4% of 641 patients experiencing no adverse effects and only 1.4% discontinuing due to side effects that resolved with dose reduction or withdrawal.
research Clinical Efficacy, Cosmetic Acceptability, and Local Tolerability of a New Formulation of Topical 5% Minoxidil without Propylene glycol: A 6-month, Multicentre, Real-life, Prospective, Assessor-Blinded Study in 196 Subjects with Hair Loss. The andldquo;NOMINALandrdquo; Trial
This study found that a new propylene glycol-free 5% minoxidil lotion demonstrated good clinical efficacy and very good cosmetic acceptability and tolerability after six months of use in patients with androgenetic alopecia, showing results comparable to traditional formulations containing propylene glycol.
research Aromatic C-nitrosation of a bioactive molecule. Nitrosation of minoxidil
Minoxidil reacts to nitrosation 7 times more than phenol, mainly due to its -NH₂ groups, leading to the creation of N-nitrosominoxidil.
research Refractory shock following ingestion of topical minoxidil solution
This report describes a case of refractory shock and pulmonary edema resulting from the accidental ingestion of topical minoxidil, highlighting a rare instance of poisoning.
research Mechanism exploration of the combined use of minoxidil with natural compounds ginsenoside Rg3 and glycyrrhizic acid for enhancing androgenic alopecia therapy
In mouse studies, this research found that combining ginsenoside Rg3 and glycyrrhizic acid with minoxidil improved treatment outcomes for androgen alopecia by addressing both symptoms and root causes, notably activating the Wnt/β-catenin pathway and promoting hair follicle cell proliferation.
research Machine Learning Guided Discovery of Superoxide Dismutase Nanozymes for Androgenetic Alopecia
This study found that a microneedle patch using manganese thiophosphite showed greater hair regrowth potential compared to minoxidil, even with less frequent application, for treating androgenetic alopecia.
research Green‐Prepared Magnesium Silicate Sprays Enhance the Repair of Burn‐Skin Wound and Appendages Regeneration in Rats and Minipigs
This study suggests that inorganic magnesium silicate sprays can improve burn wound repair and promote regeneration of skin appendages, showing superior results compared to commercial wound healing products in animal models.
research Cellulose nanocrystal-stabilized Pickering emulsion gels as vehicles for follicular delivery of minoxidil
This study reported that newly developed minoxidil Pickering emulsion gels, designed using cellulose stabilizers, showed promising results for promoting hair regrowth and targeting hair follicles by enhancing the delivery and stabilization properties of the formulation in a hair loss treatment context.
research Sodium alginate cross-linked hydroxypropyl methylcellulose/hydroxyapatite nano biomaterial mediated with zinc to promote bone tissue healing
This research developed a zinc-doped nanocomposite using biodegradable materials, observing effective bone targeting and regeneration capabilities in vivo, with no observed cytotoxicity in the MG63 cell line, potentially due to blocking Farnesyl Diphosphate Synthetase to inhibit osteoclastic activity and promote osteogenesis.
research The Trilogy of Skin Regeneration via Metal-Organic Frameworks Nanomedicine: Precision Management of Refractory Wounds, Pathological Scarring, and Hair Follicle Reactivation
This review discusses metal-organic frameworks for treating diabetic infected wounds and related applications, reporting no new clinical results but highlighting challenges like biosafety and production for future research.