Oral Minoxidil Efficacy And Safety In Male Androgenetic Alopecia: A Literature Review

    June 2026 in “ International Journal of Innovative Technologies in Social Science ”
    Maciej Makarewicz, Grzegorz Jałoszyński, Oliwia Marciniak … Marcin Patryk Barbachowski
    Studysummary This review concluded that low-dose oral minoxidil is an effective and well-tolerated treatment for male androgenetic alopecia, with significant hair density improvements and manageable side effects.
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    Research cited in this study 17

    1. Expanding the Therapeutic Landscape of Minoxidil for Androgenetic Alopecia: Topical, Oral and Sublingual Formulations Frontiers in Pharmacology · 2026
    2. Oral Minoxidil for Alopecia Treatment: Risks, Benefits, and Recommendations American Journal of Clinical Dermatology · 2025
    3. Efficacy and Safety of Oral Minoxidil in the Treatment of Alopecia: A Single-Arm Rate Meta-Analysis and Systematic Review Frontiers in Pharmacology · 2025
    4. Characterization and Management of Adverse Events of Low-Dose Oral Minoxidil Treatment for Alopecia: A Narrative Review Journal of Clinical Medicine · 2025
    5. Low-Dose Oral Minoxidil Initiation for Patients With Hair Loss JAMA Dermatology · 2024
    6. Oral Minoxidil Versus Topical Minoxidil for Male Androgenetic Alopecia JAMA dermatology · 2024
    7. New Target for Minoxidil in the Treatment of Androgenetic Alopecia Drug Design Development and Therapy · 2023
    8. Oral Minoxidil Use in Androgenetic Alopecia and Telogen Effluvium Archives of Dermatological Research · 2022
    9. Relative Efficacy of Minoxidil and the 5-Alpha Reductase Inhibitors in Androgenetic Alopecia Treatment of Male Patients JAMA Dermatology · 2022
    10. Review of Oral Minoxidil as Treatment of Hair Disorders: In Search of the Perfect Dose 2021
    11. Safety of Low-Dose Oral Minoxidil for Hair Loss: A Multicenter Study of 1404 Patients Journal of The American Academy of Dermatology · 2021
    12. Efficacy and Safety of Oral Minoxidil 5 mg Once Daily in the Treatment of Male Patients with Androgenetic Alopecia: An Open-Label and Global Photographic Assessment Dermatology and therapy · 2020
    13. Safety of Low-Dose Oral Minoxidil Treatment for Hair Loss: A Systematic Review and Pooled Analysis of Individual Patient Data Dermatologic Therapy · 2020
    14. Oral Minoxidil Treatment for Hair Loss: A Review of Efficacy and Safety Journal of The American Academy of Dermatology · 2020
    15. Low-Dose Oral Minoxidil as Treatment for Non-Scarring Alopecia: A Systematic Review International Journal of Dermatology · 2020
    16. Very-Low-Dose Oral Minoxidil in Male Androgenetic Alopecia: A Study with Quantitative Trichoscopic Documentation Journal of The American Academy of Dermatology · 2019
    17. Treatment of Hair Loss The New England Journal of Medicine · 1999