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The update highlights that non-classic congenital adrenal hyperplasia is common in women with excess male hormones, requires specific hormone tests for diagnosis, and has various treatment options depending on age and symptoms.

Some systemic treatments work for nail psoriasis but can have serious side effects.

Some drugs may reduce prostatitis symptoms short-term with few side effects.

Cannabinoids may help treat chronic and chemotherapy-induced neuropathic pain, but more research is needed to confirm their effectiveness and safety.

Certain genetic variations are linked to increased androgen levels in PCOS, but more research is needed to understand these connections fully.

Hormone therapies like birth control pills and spironolactone are safe and effective for treating women's adult acne.

Adults with certain skin conditions may have higher levels of inflammation in their body.

For women with moderate to severe unwanted hair growth or acne, birth control pills are the first choice, with other medications like cyproterone, spironolactone, flutamide, or finasteride as alternatives, and permanent hair removal should be done with electrolysis or laser.

The document concludes that PCOS has a strong genetic component, but more research is needed to fully understand the specific genes involved.

Low-level laser therapy can stimulate hair growth more effectively than fake devices, but patient satisfaction is similar for both. Results should be taken with caution due to small study sizes and differences between studies. More research is needed.

Researchers found two new genetic variants linked to Alzheimer's disease.

Hormone therapy may increase migraines in transgender women and decrease them in transgender men; more research is needed on migraine management in transgender individuals.

AGA patients have higher heart disease risk.

Many children and teens referred to gender services receive hormone treatments, but more research is needed on their long-term care and outcomes.

Some treatments for severe hair loss work but often have side effects, with baricitinib showing the most promise.

Apremilast shows promise for several skin conditions but needs more research.

Women with nonclassical congenital adrenal hyperplasia may have a higher risk of fertility issues and miscarriages, and should get genetic counseling.

Long-term estrogen therapy in postmenopausal women can improve certain health markers, hair loss is common regardless of hormone use, stopping estrogen doesn't increase breast cancer risk, smoking does, and a balanced BMI is linked to lower mortality.

AA patients with comorbid conditions face more severe hair loss and need specific treatments.

Early-onset baldness is linked to genetics, lifestyle, and can indicate higher risk for heart and metabolic diseases, and affects mental health.

Heavy metals like arsenic, cadmium, and lead can increase cancer risk and worsen outcomes.

Women with PCOS are at higher risk for gum disease, and managing shared risk factors can help both conditions.

The document concludes that careful history and physical exams are crucial for accurately diagnosing polycystic ovary syndrome and distinguishing it from other similar conditions.

Minoxidil and photobiomodulation together improve hair growth better than minoxidil alone.

Mice without the vitamin D receptor have bone issues and other health problems, suggesting vitamin D is important for preventing various diseases in humans.

The Rotterdam Study investigates diseases in older adults and has produced many research findings.

The European Society of Endocrinology advises individualized long-term management for PCOS, focusing on lifestyle changes, accurate diagnosis, and treatments for associated health risks and symptoms.

Dehydroepiandrosterone (DHEA) is a prohormone important for producing sex steroids and has potential health benefits.

The guidelines suggest lifestyle changes, diet adjustments, and personalized medication to manage dyslipidemia and reduce heart disease risk.

The bulletin provides guidelines for diagnosing and managing PCOS, suggesting weight loss, hormonal contraceptives, and diabetes screening, with clomiphene for infertility and various treatments for excess hair.