16 citations
,
May 2020 in “Frontiers in pharmacology” This study found that minoxidil stimulates the Kir6.2/SUR2 potassium channel, leading to tumor growth arrest in an ovarian cancer xenograft model by disrupting mitochondrial function and inducing cell death.
25 citations
,
November 1987 in “British Journal of Dermatology” This study observed increases in scalp blood flow following the application of 3% minoxidil and 0.1% hexyl nicotinate in individuals with alopecia.
June 2010 in “Chin J Postgrad Med” In this study, prednisone and zinc preparation combined with 2% minoxidil significantly improved curative rates for androgenetic alopecia after 9 to 12 months compared to prednisone and zinc preparation alone.
5 citations
,
January 2011 This study found that Gyungohkgo-gamibang extract and minoxidil both significantly stimulated hair growth and increased hair density and thickness in C57BL/6 mice compared to a vehicle treatment.
May 2024 in “Anais brasileiros de dermatologia/Anais Brasileiros de Dermatologia” Oral minoxidil 7.5 mg for hair loss increases heart rate but not blood pressure.
This study discusses a potential new treatment called AMPLEX PLUS that may significantly slow hair loss and stimulate new hair growth by influencing the transition of hair follicles from the telogen phase to the active anagen phase.
11 citations
,
September 1988 in “Annals of Plastic Surgery” This review discusses topical minoxidil for hair growth, reporting about one-third of users gain new hair, noting diminished effects after a year and increased hair loss if stopped, but provides no new experimental results.
July 2026 in “Experimental Dermatology” In this study, researchers found that minoxidil sulfate enhances the anti-inflammatory effects of the JAK inhibitor baricitinib in alopecia areata, modulating inflammatory signals and preserving immune privilege features in human hair cells, which suggests potential benefits for combined therapy.
September 2025 in “International Journal of Innovative Technologies in Social Science” This study found that low-dose oral minoxidil (≤5 mg/day) effectively increased hair number and diameter in men and women with androgenetic alopecia, and was generally well-tolerated with mostly mild adverse effects, although serious complications were rare and associated mainly with pre-existing heart conditions.
January 2025 in “Reactions Weekly” November 2024 in “Reactions Weekly” May 2023 in “Reactions Weekly”
February 2024 in “PubMed” This study reported that minoxidil lotions produced using a propylene glycol-free base, Aloplus Total, demonstrated high minoxidil solubility and maintained chemical and physical stability for over 180 days, suggesting suitability for enhanced topical treatments of androgenetic alopecia.
2 citations
,
March 1988 in “Archives of Dermatology” Minoxidil can help regrow hair or slow down hair loss, but results vary among individuals.
October 2022 in “Zenodo (CERN European Organization for Nuclear Research)” This article reviews the benefits of Truman Plus Male Enhancement for testosterone levels and sexual health, but it does not present any new clinical study results.
14 citations
,
March 2015 in “Clinical and Experimental Dermatology” In this study, human placenta extract was observed to enhance the hair-growth-promoting effects of minoxidil and stimulate earlier and prolonged anagen phases in a mouse model.
4 citations
,
December 2012 in “PubMed”
24 citations
,
May 1982 in “Biochemical Pharmacology” These drugs cause hair growth without affecting testosterone or adrenal hormones.
April 2025 in “Skin Health and Disease” This systematic review found that both oral and topical minoxidil have similar efficacy in improving hair density and terminal hair density among patients with androgenetic alopecia, suggesting that oral minoxidil may be a viable second-line or adjunct treatment option.
3 citations
,
May 2020 in “Journal of The European Academy of Dermatology and Venereology” This paper introduces a novel topical booster aimed at enhancing follicular sulfotransferase activity to potentially improve minoxidil response in patients with androgenetic alopecia but reports no new clinical results.
88 citations
,
February 2011 in “Journal of Dermatological Science” This study found that topical minoxidil modestly extended the anagen phase in mice by activating β-catenin activity in dermal papilla cells.
152 citations
,
April 2012 in “Recent Patents on Inflammation & Allergy Drug Discovery” This review describes minoxidil's hair regrowth mechanism and discusses dermatological applications, but reports no new clinical results, emphasizing the need for regular use and addressing allergic reactions.
September 2023 in “Journal of Cosmetic Dermatology” This study concluded that topical minoxidil could effectively accelerate nail growth in both healthy individuals and those with nail disorders, though the regimen might differ across these groups.
August 2023 in “Journal of Cosmetic Dermatology” This study characterized the activity of naturally occurring minoxidil sulfotransferase enzymes in various plants and found that seven out of ten botanical extracts showed significant activity, suggesting these could potentially enhance minoxidil response in treating androgenetic alopecia.
March 2023 in “Asian Journal of Beauty and Cosmetology” This study found that the herbal extract HX109 promoted hair growth in mice by increasing cell viability and enhancing hair regrowth, with the effects increasing as doses rose.
April 2025 in “Archives of Dermatological Research” The combination of finasteride and minoxidil is as safe and effective as minoxidil alone for improving hair growth in men.
January 2025 in “Open Science Framework” The project aims to validate a nutritional intervention targeting the Redox–NO–Androgen Axis to restore mitochondrial, endothelial, and hormonal balance in male health disorders related to oxidative stress.
12 citations
,
June 2017 in “Cell Cycle” This study observed that 5% minoxidil topical foam alters gene expression and signaling pathways in the scalp, providing insights into its mechanism of action in men with androgenetic alopecia.
1 citations
,
March 2021 in “CRC Press eBooks” This article discusses androgenetic alopecia and its treatments, including the barriers and adverse effects associated with topical minoxidil, but reports no new clinical findings.
34 citations
,
February 1992 in “The Journal of Clinical Endocrinology and Metabolism” In this study, the combination of finasteride and minoxidil significantly increased hair growth in balding male stumptail macaques compared to each drug alone.