Topical Minoxidil for Nail Growth: A Conventional Medication with a Novel Indication

    September 2023 in “ Journal of Cosmetic Dermatology
    Parvaneh Hatami, Zeinab Aryanian, Hamed Nicknam Asl, Azadeh Goodarzi, Dorsa Hatami
    From the encyclopedia
    Biotin →

    supplement to help with hair texture and quality

    Minoxidil →

    An essential vasodilator with some anti-androgenic effects

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    Studysummary This study concluded that topical minoxidil could effectively accelerate nail growth in both healthy individuals and those with nail disorders, though the regimen might differ across these groups.
    Our plain-language summary. Not medical advice or a treatment recommendation. Consult a qualified healthcare professional before changing treatment. Full disclaimer
    Topical minoxidil, commonly used for treating androgenetic alopecia, could potentially be a useful agent for accelerating nail growth in both healthy and diseased nails, according to a recent study. The study found that minoxidil increases cutaneous blood flow, which could positively affect nail growth rate. A quasi-experimental study on 38 healthy volunteers showed a positive effect of topical minoxidil on nail growth rate. However, the combination of minoxidil and biotin resulted in lesser longitudinal nail growth, possibly due to the limited capacity of the nail matrix in producing material. Another study on 50 patients with a total of 84 affected toenails showed a weak, but significant clinical effect of daily application of minoxidil. The authors suggest that further prospective controlled studies with larger sample sizes are needed to better understand the clinical effects and long-term side effects of using topical minoxidil for nail growth.
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