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The Rotterdam Study updated findings on elderly health, focusing on heart disease, genetics, lifestyle effects, and disease understanding.

Calreticulin has roles in healing, immune response, and disease beyond its known functions in the endoplasmic reticulum.

The Endocrine Society advised against routine testosterone therapy for women, citing a need for more research on long-term safety and a clear definition of androgen deficiency.

The Rotterdam Study aims to understand disease causes in the elderly and has found new risk factors and genetic influences on various conditions.

PCOS is a complex disorder in women that can lead to various health risks and requires personalized treatment.

The immune system plays a key role in tissue repair, affecting both healing quality and regenerative ability.

The guidelines advise against using testosterone and DHEA in women for most conditions due to safety and effectiveness concerns, but suggest considering testosterone for postmenopausal women with low sexual desire.

Diagnosing PCOS in teenagers is challenging and should use strict criteria to avoid misdiagnosis and unnecessary worry.

Lactate production is important for activating hair growth stem cells.

Hair stem cell regeneration is controlled by signals that can explain different hair growth patterns and baldness.

Women with PCOS face higher risks of diabetes and heart disease, and these risks increase with obesity.

Fat cells in the skin help start healing and form important repair cells after injury.

Macrophages help regrow hair by activating stem cells using AKT/β-catenin and TNF.

TSH is usually the only test needed to check thyroid function in primary care.

The document concludes that proper diagnosis and a multidisciplinary approach are crucial for managing Congenital Adrenal Hyperplasia effectively.

Nanoparticles can improve skin treatments by better targeting hair follicles, but more research is needed for advancement.

Finasteride helps regrow hair and shrink prostate by reducing DHT, with some sexual side effects.

The document concludes that early diagnosis and treatment of Congenital Adrenal Hyperplasia are crucial for preventing serious health issues and improving patient outcomes.

MDP hydrogel heals wounds faster and better than other treatments in diabetic mice.

Inherited ichthyoses cause widespread skin scaling and thickening due to gene mutations.

Stress hormone corticosterone blocks a growth factor to slow down hair stem cell activity and hair growth.

Beta-caryophyllene helps improve wound healing in mice, especially in females.

Some parents have a mild form of congenital adrenal hyperplasia without symptoms, and they usually don't need treatment.

The new micelle formulation delivers acne treatment more effectively and safely than current gels.

Blocking BACE1 and BACE2 enzymes causes hair color loss in mice.

Products should be called 'sperm-safe' only after thorough, well-designed tests.

Mutations in the LSS gene cause a rare type of hereditary hair loss.

Nonclassic adrenal hyperplasia is a genetic condition that can cause early puberty and fertility problems, treated with specific steroids.

Human hair contains diverse proteins, including keratins and histones, which could help assess hair health and aging.

Glutamine metabolism affects hair stem cell maintenance and their ability to change back to stem cells.