TLDR Daughters of women with PCOS generally experience normal puberty but may have more body hair and different body fat distribution.
The study with 76 daughters of mothers with PCOS and 80 daughters of control mothers found that pubertal development in daughters of women with PCOS was largely similar to that of daughters of control mothers. There were no significant differences in most reproductive and metabolic characteristics, including urinary gonadotropins, sex steroids, salivary insulin levels, body composition, or ovarian volume. However, daughters of PCOS mothers had a higher incidence of hirsutism (69% in Tanner 4/5) compared to control daughters (31%) and an increased android/gynoid fat ratio in Tanner stages 2/3. The study concluded that daughters of PCOS mothers may not require excessive evaluation and intervention if asymptomatic, but it noted limitations such as potential bias, the cross-sectional nature of the study, and the lack of racial and ethnic diversity in the sample. Further research with larger and more diverse samples was recommended.
1265 citations,
October 2013 in “The Journal of Clinical Endocrinology and Metabolism” The guideline suggests using specific criteria to diagnose PCOS, recommends various treatments for its symptoms, and advises screening for related health issues.
73 citations,
June 2008 in “The Journal of Clinical Endocrinology and Metabolism” Polycystic ovarian shape is a genetic sign of PCOS and its hormonal and metabolic features can be inherited.
270 citations,
April 2007 in “The Journal of Clinical Endocrinology and Metabolism” Women with PCOS often have more belly fat and higher insulin levels, but belly fat isn't the only cause of their insulin resistance.
75 citations,
June 1999 in “Pediatric Clinics of North America” The document concludes that early recognition and treatment of PCOS in adolescents is crucial for managing symptoms and long-term health risks.
2 citations,
December 1994 in “The Journal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism” The treatment effectively reduced hair growth and was safe for patients with PCOS, but it needs better bleeding control.
97 citations,
July 2006 in “Dermatologic therapy” The document concludes that accurate diagnosis and personalized treatment are important for skin problems in women with PCOS.
1 citations,
June 2019 in “Innovare journal of medical sciences” Polycystic Ovary Syndrome (PCOS) is a hormonal disorder in women that can cause infertility and other health issues, and it may be improved by treatments that increase insulin sensitivity.
42 citations,
January 2006 in “Obstetrical & Gynecological Survey” The document concludes that correct diagnosis and management of PCOS are important, and more research is needed on its risks and treatments.
