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P-cadherin is important for hair growth and health, and its problems can cause hair and skin disorders.

Diabetes can lead to blindness and skin problems, and managing blood sugar and blood pressure is crucial to prevent these complications.

A 10-year-old boy had the earliest reported case of hair that became progressively kinkier but eventually returned to normal on its own.

Aleglitazar and its major metabolite are safe enough to proceed to Phase 3 clinical trials.

Discoid Lupus Erythematosus often causes scarring hair loss, is influenced by genetics and environment, and requires early treatment to prevent worsening.

PEGylated liposomal doxorubicin improves cancer treatment effectiveness and reduces side effects like heart damage and hair loss.

The document concludes that permanent hair loss conditions are complex, require early specific treatments, and "secondary permanent alopecias" might be a more accurate term than "secondary cicatricial alopecia."

EDA signaling is linked to skin disorders, various cancers, and liver disease.

Cell polarity signaling controls tissue mechanics and cell fate, with complex interactions and varying pathways across species.

New treatments for skin damage from UV light using stem cells and their secretions show promise for skin repair without major risks.

B2m-free HLA variants may be a new class of HLA important in immune responses and diseases.

The protein p21 is more abundant in normal skin cells than in melanoma cells and may help protect against melanoma, with UVB light affecting its levels.

Androgen suppression therapy (AST) doesn't significantly lower bladder cancer risk, but using finasteride, a type of AST, might decrease the risk. AST also lessens the chance of cancer coming back but doesn't really affect survival rates. More research is needed to understand AST's benefits for different bladder cancers.

Plant-based compounds might be effective, low-side-effect treatments for prostate cancer by blocking a specific enzyme.

The reviewers suggest major revisions for clarity and inclusion of recent findings on inflammation's role in cancer.

An 84-year-old man developed a rare scalp condition from a cancer drug but continued treatment as it was otherwise well tolerated.

Reviewers suggest clarifying the abstract, adding background on inflammation's effect on cancer, discussing immune cell roles, including counter studies, and correcting grammar.

Colorectal cancer development involves both genetic changes and epigenetic alterations like DNA methylation and microRNA changes.

Disrupting the Flcn gene in mice causes early kidney cysts and tumors, which can be treated with rapamycin.

VDC-1101 shows potential as a treatment for canine cutaneous T-cell lymphoma.

TGM3 is important for skin and hair structure and may help diagnose cancer.

New treatments improved blood pressure control in patients with resistant hypertension.

New treatments like nanotechnology show promise in improving skin cancer therapy.

5 alpha-reductase inhibitors like finasteride may lower prostate cancer risk and improve cancer screening.

Drinking a lot of alcohol increases the risk of prostate cancer and can worsen the condition.

Blocking YAP/TAZ could be a new way to treat skin cancer.

Overexpression of HDGF in melanocytes does not cause cancer.

Mesenchymal Stem/Stromal Cells (MSCs) help in wound healing and tissue regeneration, but can also contribute to tumor growth. They show promise in treating chronic wounds and certain burns, but their full healing mechanisms and potential challenges need further exploration.

The reviewers found the manuscript on inflammation's role in cancer stem cells to be relevant but suggested it needs clarity, more background information, discussion on immune cells' role in tumors, updated references, and grammar corrections.

The reviewers suggest clarifying the abstract, adding background on inflammation's effect on stem cells and cancer, discussing immune cells' role in tumors, and considering inflammation's potential to reduce cancer growth.