May 2017 in “Endocrine Abstracts” Men with early hair loss and certain health factors may have a higher risk of developing reproductive issues, similar to polycystic ovary syndrome in women.
308 citations,
December 2018 in “PLOS Genetics” The research found that PCOS has common genetic factors regardless of how it is diagnosed and is linked to metabolic and reproductive issues.
295 citations,
September 2006 in “Cell Cycle” The conclusion is that using drugs to block the TOR pathway might slow aging and prevent age-related diseases.
137 citations,
March 2006 in “Cns Drug Reviews” Finasteride treats enlarged prostate and hair loss, but may cause side effects in some patients.
88 citations,
May 2005 in “Journal of Dermatological Science” Versican, a protein, is less present in thinning hair follicles and this decrease might contribute to common hair loss in men.
72 citations,
January 2011 in “Current Pharmaceutical Design” S5αR inhibitors might help treat schizophrenia and other mental disorders but need more research.
50 citations,
May 2020 in “Journal of Clinical Medicine” Non-binary transgender individuals need personalized hormonal treatments for better well-being and quality of life.
36 citations,
September 2015 in “Forensic Science International: Genetics” Certain DNA variants can predict straight hair in Europeans but are not highly specific.
32 citations,
January 2018 in “American Journal of Clinical Dermatology” Hormone therapy affects hair growth in transgender individuals, with testosterone potentially causing hair loss in trans men and estrogen reducing facial/body hair in trans women; treatment options vary.
31 citations,
September 2008 in “International Journal of Andrology” 5-alpha-reductase inhibitors may cause a low incidence of erectile dysfunction that decreases over time.
28 citations,
May 1998 in “Skin Research and Technology” Scalp flaps are stiffer than skin from other body areas, which helps in planning reconstructive and cosmetic head surgeries.
27 citations,
July 2017 in “European Journal of Dermatology” Certain microRNAs are linked to various skin diseases and could be used to diagnose and treat these conditions.
25 citations,
March 2012 in “Journal of Dermatological Science” Genetic variants linked to ten skin diseases were found, showing both immune and non-immune factors play a role.
24 citations,
December 2013 in “Sexual medicine reviews” Finasteride can cause sexual problems and depression in young men.
21 citations,
April 2019 in “Endocrinology and Metabolism Clinics of North America” Transgender patients need proper skin care, especially when undergoing hormone treatments, to manage issues like acne and hair loss.
18 citations,
July 2020 in “Basic and Clinical Andrology” Wait 3 months after COVID-19 before trying assisted reproduction and further research is needed on COVID-19's effects on male hormones and fertility.
14 citations,
April 2020 in “Journal of Cosmetic Dermatology” QR678 treatments were more effective and comfortable for male hair loss than PRP treatments.
14 citations,
June 2014 in “Journal of Pharmaceutical Sciences” Formulation P-08-016 better targets hair follicles for baldness treatment.
14 citations,
May 2011 in “Drug Metabolism and Disposition” Ketoconazole increases finasteride's effectiveness and lifespan in the body.
13 citations,
February 2016 in “Clinical Medicine” The document concludes that diagnosing and treating hair loss is complex and requires understanding its psychological effects and underlying causes, while also calling for more research and new treatments.
12 citations,
August 2013 in “Facial Plastic Surgery Clinics of North America” Choose hair restoration surgery candidates carefully and plan treatments for a natural look and future hair loss.
9 citations,
August 2013 in “PLOS ONE” Genetic variants at 20p11 increase baldness risk in Chinese Han people.
8 citations,
February 2017 in “Clinical Drug Investigation” Finasteride can cause sexual dysfunction and depression, which may persist and require hormonal treatment.
8 citations,
July 2012 in “Cambridge University Press eBooks” Androgens can both increase body hair and cause scalp hair loss.
7 citations,
March 2020 in “Lasers in Medical Science” LLLT is a safe, promising hair loss treatment, but more research needed.
5 citations,
December 2021 in “Physiological Research” Men, particularly those with hair loss, are more likely to get the virus, and those with prostate cancer may have milder symptoms. Testosterone's role in the disease is unclear, and the virus doesn't seem to harm male fertility. Women with PCOS might be at higher risk. More research is needed.
3 citations,
February 1996 in “Dermatologic Surgery” Walter P. Unger suggests using advanced hair transplant techniques for broader coverage, as they provide natural results and use donor tissue efficiently, while also recommending personalized planning due to the unpredictable progression of baldness.
2 citations,
October 2022 in “Frontiers in genetics” Late diagnosis of congenital adrenal hyperplasia can greatly affect physical development, gender identity, and sexual health.
2 citations,
April 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” MendelVar is a tool that helps identify important genes by combining GWAS data with Mendelian disease information.
2 citations,
February 2019 in “Journal of Investigative Dermatology” Higher levels of the DP2 receptor may lead to hair loss.