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This study observed that MAA beads improved vascularization in non-diabetic male mice by modulating the Shh signaling pathway in wound granulation tissue, but showed no such effects in females.

This case report details an unusual instance of multiple eruptive milia in an otherwise healthy 3-month-old baby, characterized by widespread distribution and believed to be idiopathic due to the absence of associated genodermatoses.

This study found that women with genetic hair loss experienced significant improvements in hair density, count, and thickness when treated with both Rehmannia root extract and microneedling therapy, with the combination showing the greatest benefits compared to each treatment alone.

In this study, melatonin-loaded Pickering emulsions stabilized by chitosan-dextran sulphate nanoparticles and enhanced with lecithin showed improved photostability, antioxidant activity, and follicular delivery in androgenic alopecia-affected rats, potentially rivaling commercial minoxidil for hair loss treatment.

This study introduces a co-design framework using finite element analysis to optimize separable bubble microneedles, demonstrating enhanced transdermal and sublingual drug delivery in preclinical models. In vivo results showed faster hair regrowth and glucose lowering in animals, indicating potential improvements over traditional methods.

This study demonstrated that human hair can be coated with Fe3O4 nanoparticles, allowing it to be oriented and moved by a magnetic field, which may enhance drug delivery and hair care applications.

This study found that a multimodal microemulsion containing minoxidil, diclofenac, and tea tree oil was significantly more effective and stable than minoxidil alone in treating androgenic alopecia over a 32-week period.

This study found that subcutaneous injections of certain chelators led to skin and hair depigmentation, increased skin elasticity, and disturbed hair growth in minks, without affecting fur quality.

This study suggests that Tenebrio molitor larvae extract may promote hair growth and prevent hair loss by enhancing cell proliferation and protecting against cytotoxicity in laboratory settings.

This study found that the new delivery system HL@Mi enhanced the skin penetration, local bioavailability, and safety of minoxidil, supporting improved hair growth in an androgenetic alopecia animal model.

This study found that mesotherapy combined with minoxidil for androgenetic alopecia shows promise with high patient satisfaction and manageable risks, though some uncommon side effects may occur.

This study found that injectable platelet-rich fibrin (iPRF) combined with microneedling is a safe and effective treatment for male androgenetic alopecia, but it currently lacks comparison data against other popular therapies.

This study found that macrophage-stimulating protein (MSP) enhanced hair growth in both human hair follicles cultured in vitro and in mice through the promotion of anagen phase induction.

In this study, microneedling combined with minoxidil solution showed a higher rate of excellent hair growth response in male androgenetic alopecia patients compared to microneedling with hair multivitamin solution, though some side effects like pain and bruising were noted.

In this study, topical application of α-methylspermidine during the telogen phase in mice induced hair growth by increasing the polyamine pool and mimicking the anagen phase's characteristics.

In this study, the authors reported that among patients with androgenetic alopecia, treatment with minoxidil 5% lotion combined with PRP and microneedling resulted in better hair growth and higher satisfaction compared to other treatment groups.

In this study, a TGF-β mimic molecule from Heligmosomoides polygyrus was observed to enhance wound healing in mice, with improved tissue regeneration and specific immune cell recruitment without increased scarring.

This study found that a new 5% minoxidil foam formulation significantly increased hair counts and improved hair loss condition in men with androgenetic alopecia over 16 weeks compared to placebo.

This meta-analysis suggests that combining minoxidil with microneedling significantly increases total hair count compared to minoxidil alone in patients with androgenetic alopecia, although it did not significantly affect hair diameter.

This study suggests that M2 macrophages play a key role in promoting wound-induced hair neogenesis in mice by producing growth factors like Igf1 and Fgf2.

This study demonstrates that encapsulating cell-free fat extract in a gelatin methacrylate hydrogel enhances flap repair by sustaining angiogenesis, reducing oxidative stress, and offering favorable biocompatibility in a murine skin flap model, thereby advancing potential clinical flap necrosis treatments.

This study evaluated the safety and efficacy of Bio-Pulsed avian mesenchymal stem cell-derived small extracellular vesicles when applied topically, finding significant improvements in hair growth, skin rejuvenation, and regenerative microRNA presence among 60 human participants without adverse events.

In this study, a home-use microneedle device combined with 5% minoxidil showed potential for enhancing hair growth in pattern hair loss over six months, although the observed improvements in hair count and patient assessments were not statistically significant compared to other treatments.

This study found that combining microneedling with 5% minoxidil improved hair growth in Chinese men with androgenetic alopecia, possibly through activating the Wnt/β-catenin signaling pathway.

Combining minoxidil with microneedling leads to better hair regrowth than using minoxidil alone.

In this case study, a 14-year-old female with premature hair graying showed improved hair color after treatment with a topical Melitane 5% formulation and oral hair supplements.

This study observed that including cationic minoxidil particles in a shampoo facilitated notable hair growth promotion despite a negative surface charge after rinsing, likely due to ionic interactions with the skin.

This review indicates that while microneedling shows potential for managing androgenetic alopecia, particularly in combination with other treatments, the existing evidence is of low to moderate quality, and more robust trials are needed to confirm its clinical efficacy and safety.

This study found that growth factor cocktail treatment including FGF9, combined with microneedling, significantly improved hair density in androgenetic alopecia patients compared to treatment with regular GFC or normal saline.