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    Glossary Lymphocytic Infiltrate

    accumulation of immune cells in tissue causing inflammation

    Lymphocytic infiltrate refers to the accumulation of lymphocytes, a type of white blood cell, in a particular tissue. This often occurs as part of the body's immune response to infection, inflammation, or autoimmune conditions, where the immune system mistakenly attacks healthy cells. In the context of hair and alopecia, lymphocytic infiltrate can be seen in conditions like alopecia areata, where these immune cells target hair follicles, leading to hair loss.

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    1. Lymphocytic Infiltration of the Skin Jessner-Kanof After Treatment With a Hydroquinone-Containing Bleaching Cream Archives of dermatology · 2006 · 20 citations
    2. Histologic features of alopecia areata other than peribulbar lymphocytic infiltrates 2011 · 53 citations
    3. Pulsed dye laser treatment of Jessner lymphocytic infiltration of the skin Journal of The American Academy of Dermatology · 2009
    4. 202 Automated assessment of tumor infiltrating lymphocytes informs mortality in thin melanoma Journal of Investigative Dermatology · 2023
    5. Alopecia areata but not androgenetic alopecia is characterized by a restricted and oligoclonal T-cell receptor-repertoire among infiltrating lymphocytes Journal of Cutaneous Pathology · 1997 · 19 citations
    6. Topical Mechlorethamine Restores Autoimmune-Arrested Follicular Activity in Mice with an Alopecia Areata-Like Disease by Targeting Infiltrated Lymphocytes Journal of Investigative Dermatology · 2003 · 19 citations
    7. Lymphocytic Mural Folliculitis Resembling Epitheliotropic Lymphoma in Tigers (<i>Panthera tigris</i>) Veterinary Pathology · 2018
    8. Human regulatory γδT lymphocytes as novel autoimmunity-protective cells: Lessons from alopecia areata 2024
    9. Diagnostic Usefulness of a Peribulbar Eosinophilic Infiltrate in Alopecia Areata JAMA Dermatology · 2014 · 19 citations
    10. Alopecia areata with lymphocytic mural folliculitis affecting the isthmus in a thoroughbred mare Veterinary Dermatology · 2004 · 14 citations
    11. 259 Immunohistochemical insight into the association between the collapse of immune privilege in the sweat gland and syringotropic immune cell infiltrates in collagen diseases Journal of Investigative Dermatology · 2017
    12. Frontal fibrosing alopecia: Histopathological and immunohistochemical study of the inflammatory infiltrate and the sebaceous gland receptors Journal of the American Academy of Dermatology · 2019
    13. Immunohistochemical analysis of T-cell subsets in the inflammatory infiltrates of alopecia areata and its comparison with androgenetic alopecia International Journal of Dermatology · 2020
    14. Alopecia Areata: A tissue specific autoimmune disease of the hair follicle Autoimmunity Reviews · 2005 · 185 citations
    15. Overview of common, rare and atypical manifestations of cutaneous lupus erythematosus and histopathological correlates Lupus · 2010 · 157 citations
    16. Frontal fibrosing alopecia versus lichen planopilaris: a clinicopathological study International Journal of Dermatology · 2006 · 126 citations
    17. Histological features of peripilar signs associated with androgenetic alopecia Archives of Dermatological Research · 2004 · 95 citations
    18. A histologic review of 27 patients with lichen planopilaris Journal of the American Academy of Dermatology · 2008 · 76 citations
    19. Permanent scalp alopecia related to breast cancer chemotherapy by sequential fluorouracil/epirubicin/cyclophosphamide (FEC) and docetaxel: a prospective study of 20 patients Annals of Oncology · 2012 · 68 citations
    20. Essential syphilitic alopecia revisited Journal of The American Academy of Dermatology · 1995 · 53 citations
    21. The Medical Treatment of Cicatricial Alopecia Seminars in Cutaneous Medicine and Surgery · 2006 · 46 citations
    22. Treatment of chronic severe alopecia areata with topical diphenylcyclopropenone and 5% minoxidil: A clinical and immunopathologic evaluation Journal of The American Academy of Dermatology · 1993 · 41 citations
    23. Cutaneous lupus erythematosus: clinico-pathologic correlation Italian Journal of Dermatology and Venereology · 2018 · 33 citations
    24. Acute hair loss on the limbs in frontal fibrosing alopecia: a clinicopathological study of two cases 2010 · 31 citations
    25. An unusual variant of granulomatous adnexotropic cutaneous T-cell lymphoma British Journal of Dermatology · 2003 · 23 citations
    26. Involvement of the bulge region with decreased expression of hair follicle stem cell markers in senile female cases of alopecia areata 2010 · 20 citations
    27. Diffuse Alopecia With Stem Cell Folliculitis American Journal of Dermatopathology · 1999 · 16 citations
    28. IMMUNOPATHOLOGY OF THE HUMAN HAIR FOLLICLE Dermatologic Clinics · 1999 · 15 citations
    29. Severe diffuse non-scarring hair loss in systemic lupus erythematosus - clinical and histopathological analysis of four cases Journal of the European Academy of Dermatology and Venereology · 2011 · 15 citations
    30. Beard involvement in a man with frontal fibrosing alopecia Indian Journal of Dermatology Venereology and Leprology · 2014 · 14 citations