Folliculotropic Mycosis Fungoides Following Renal Transplantation

September 2011 in “ Journal of the American Academy of Dermatology ”

Natalia Vlassova, Yelena M. Frankel, Manisha J. Patel, Jacqueline M. Junkins‐Hopkins, Laura Y. McGirt

TLDR A man developed a skin cancer called folliculotropic mycosis fungoides after a kidney transplant.

A 46-year-old Caucasian man developed folliculotropic mycosis fungoides (FMF), a type of cutaneous T-cell lymphoma, two years after a renal transplant. His symptoms included eczematous, erythematous plaques, perifollicular pustules, and furuncles. Histopathology revealed a lymphocytic infiltrate with follicular mucinosis and atypical lymphocytes. Immunophenotyping showed a CD3+ infiltrate with loss of CD7 and intact CD5, and some cells were positive for Epstein-Barr virus (EBV). A clonal T-cell receptor gamma gene pattern confirmed the diagnosis, which was consistent with post-transplant lymphoproliferative disorder (PTLD). Flow cytometry of peripheral blood showed no abnormal population.

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