Acral Lymphomatoid Papulosis in a 31-Year-Old Woman
February 2010
in “
Journal of The American Academy of Dermatology
”
TLDR A woman had a rare skin condition with recurring painful nodules that heal in 6 weeks, often without needing treatment.
A 31-year-old woman presented with painful, ulcerated nodules on her hand, diagnosed as acral lymphomatoid papulosis, a rare form of lymphomatoid papulosis. Histological examination showed a dense lymphocytic infiltrate with CD30+ cells. Over 2 years, she experienced recurrent lesions that ulcerated and resolved in 6 weeks, sometimes treated with corticosteroids for faster healing. Lymphomatoid papulosis is a CD30+ lymphoproliferative disorder with three histologic subtypes, and the prognosis is generally excellent, though patients have an increased risk of developing other malignancies. There are no curative therapies, and treatment is often unnecessary for infrequent lesions.
