25 citations,
July 2016 in “The journal of investigative dermatology/Journal of investigative dermatology” Imiquimod cream activates hair follicle stem cells and causes early hair growth by changing immune cells and certain protein expressions.
9 citations,
June 1999 in “Journal of Investigative Dermatology” The HPV type 11 region activates hair-specific gene expression in mice.
25 citations,
June 2014 in “Journal of Endocrinology/Journal of endocrinology” Human sebaceous glands contain enzymes that affect androgen production and may influence sebum production and acne.
1 citations,
August 2022 in “Frontiers in Physiology” Finasteride may help treat kidney disease caused by a high-fat diet by reducing harmful toxins and improving gut bacteria.
7 citations,
January 2019 in “Annals of dermatology/Annals of Dermatology” Synthetic ceramides may help hair growth by boosting cell growth in hair follicles.
3 citations,
January 2018 in “Reproduction, Fertility and Development” Birth control pills increase certain receptor activities in female gerbil prostate glands and can lead to prostate changes.
58 citations,
February 2016 in “Scientific reports” Blocking BACE1 and BACE2 enzymes causes hair color loss in mice.
47 citations,
March 2016 in “Journal of dermatology” Understanding the genetics of rare inherited ichthyosis syndromes is key for better treatments and genetic counseling.
7 citations,
August 2021 in “Pharmaceutics” Freeze-dried dexamethasone nanoparticles in a hydrogel are stable and effective for treating alopecia areata.
October 2018 in “InTech eBooks” The gene Foxn1 is important for hair growth, and understanding it may lead to new alopecia treatments.
47 citations,
March 2017 in “Materials Science and Engineering: C” Human amniotic membrane helps heal skin wounds faster and with less scarring.
16 citations,
September 2018 in “Scientific reports” Scientists created keratinocyte cell lines from human hair that can differentiate similarly to normal skin cells, offering a new way to study skin biology and diseases.
24 citations,
September 2018 in “Journal of Materials Science: Materials in Medicine” Hyaluronic acid-based HA2 hydrogel helps heal skin wounds better with less scarring.
22 citations,
January 2008 in “Physiological Research” Steroid sulfatase is important for activating hormones that affect memory, brain function, and certain diseases, and could be a target for treating hormone-related disorders.
Autophagy helps activate hair stem cells and hair growth by changing their energy use to glycolysis.
October 2022 in “Biomedicines” Finasteride in male rats causes liver and metabolic issues in their offspring.
9 citations,
May 2021 in “BioMed research international” Human hair-derived particles can effectively carry and release the cancer drug Paclitaxel in a pH-sensitive manner, potentially targeting cancer cells while sparing healthy ones.
31 citations,
November 2015 in “PloS one” Reducing Tyrosinase prevents mature color pigment cells from forming in mouse hair.
August 2024 in “Drug Design Development and Therapy” Decursin shows promise for treating cancer, neuroprotection, inflammation, and hair loss.
10 citations,
May 2018 in “Nutrition and Cancer” Certain spices may help prevent and treat skin cancer, but more human trials are needed.
July 2024 in “Clinical Cosmetic and Investigational Dermatology” Non-drug therapies show promise for hair regrowth but need more research.
9 citations,
January 2005 in “Experimental dermatology” Melatonin receptors in hair follicles help regulate hair growth and could treat hair loss.
479 citations,
January 2005 in “BioEssays” Hair follicle development is controlled by interactions between skin tissues and specific molecular signals.
262 citations,
May 2017 in “Nanomedicine” New nanofiber technology improves wound healing by supporting cell growth and delivering treatments directly to the wound.
4 citations,
February 2021 in “Nano select” MSC-Exos can aid organ development and offer therapeutic benefits for various conditions.
May 2023 in “International journal of molecular sciences” The ABCA4 gene protects hair follicle stem cells from toxic vitamin A byproducts.
June 2024 in “International Journal of Nanomedicine” CRISPR/Cas9 has improved precision and control but still faces clinical challenges.
29 citations,
June 2020 in “International Journal of Molecular Sciences” Notch signaling disruptions can cause various skin diseases.
75 citations,
January 2009 in “International journal of trichology” Hair grays due to oxidative stress and fewer functioning melanocytes.
8 citations,
October 2020 in “Stem cell research & therapy” DNMT1 helps turn hair follicle stem cells into fat cells by blocking a specific microRNA.