The Physicochemical, Biopharmaceutical, and In Vitro Efficacy Properties of Freeze-Dried Dexamethasone-Loaded Lipomers

    August 2021 in “ Pharmaceutics
    Eloy Pena-Rodríguez, Aida Mata-Ventosa, Laura Garcia-Vega … Francisco Fernández-Campos
    Studysummary This study explored the use of dexamethasone-loaded polymer hybrid nanoparticles in a xanthan gum hydrogel for treating alopecia areata, finding that freeze drying with sucrose influenced particle size, release, and permeation, but had no impact on cytotoxicity or anti-inflammatory efficacy in human keratinocytes.
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    Research cited in this study 5

    1. Alopecia Areata: Current Status and Perspectives Archivos Argentinos de Pediatria · 2017
    2. Management of Alopecia Areata: Updates and Algorithmic Approach Journal of dermatology · 2017
    3. Delivery and Targeting of Nanoparticles into Hair Follicles Therapeutic Delivery · 2014
    4. Overview of Alopecia Areata ˜The œjournal of investigative dermatology. Symposium proceedings/˜The œJournal of investigative dermatology symposium proceedings · 2013
    5. Targeting to the Hair Follicles: Current Status and Potential Journal of dermatological science · 2010