7 citations
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August 2021 in “Pharmaceutics” This study explored the use of dexamethasone-loaded polymer hybrid nanoparticles in a xanthan gum hydrogel for treating alopecia areata, finding that freeze drying with sucrose influenced particle size, release, and permeation, but had no impact on cytotoxicity or anti-inflammatory efficacy in human keratinocytes.
15 citations
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February 2023 in “Colloids and surfaces. B, Biointerfaces” In this study using a porcine skin model, the researchers reported that smaller curcumin nanocrystals in xanthan gum gel showed higher passive skin penetration, while larger particles achieved deeper follicular accumulation.
July 2023 in “International Journal of Cosmetic Science” This article reviews how biopolymers are utilized in cosmetics, highlighting their biodegradable and non-toxic properties, recent structural developments, novel applications, and safety considerations in the formulation of skin, hair, and oral care products.
May 2026 in “Organoid Research” This review discusses recent advancements in hair follicle organoid technology for alopecia treatment but presents no new experimental results, emphasizing the potential for clinical applications and drug screening.
January 2026 in “RSC Advances” This study found that the natural polymer-based hydrogel Gel/SA@PL released growth factors in a controlled way, which enhanced tissue regeneration and minimized scarring in the healing of diabetic wounds.