research Non-Invasive Human Skin Transcriptome Analysis Using mRNA in Skin Surface Lipids
The conclusion is that analyzing RNA from skin oils is a promising way to understand skin diseases.
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research Non-Invasive Human Skin Transcriptome Analysis Using mRNA in Skin Surface Lipids
A new non-invasive method can analyze skin mRNA to understand skin diseases better.
research Transepidermal UV Radiation of Human Scalp Skin Induces Distinctive Hair Follicle Damage, Mitigated by Topical Caffeine Treatment
Caffeine can protect scalp hair follicles from damage caused by UV radiation.
research Comparative Transcriptome Profiling Provides New Insights Into Mechanisms of Androgenetic Alopecia Progression
AGA progression involves increased lipid synthesis, electron transport, and hair follicle miniaturization.
research Runx1 Role in Epithelial and Cancer Cell Proliferation Implicates Lipid Metabolism and SCD1 and SOAT1 Activity
Runx1 controls fat-related genes important for normal and cancer cell growth, affecting skin and hair cell behavior.
research Convergent Decay of Skin-Specific Gene Modules in Pangolins
Pangolins have lost some skin-related genes, but kept others, showing complex skin evolution.
research Expression of Steroidogenic Enzymes in Human Sebaceous Glands
Human sebaceous glands contain enzymes that affect androgen production and may influence sebum production and acne.
research Application of Multi-Omics Techniques to Androgenetic Alopecia: Current Status and Perspectives
Multi-omics techniques help understand the molecular causes of androgenetic alopecia.
research Genetic Ablation of Myelin Protein Zero-Like 3 in Mice Increases Energy Expenditure, Improves Glycemic Control, and Reduces Hepatic Lipid Synthesis
Removing myelin protein zero-like 3 in mice leads to better metabolism and resistance to obesity.
research Gene Network Analysis Reveals Candidate Genes Related to Hair Follicle Development in Sheep
Key genes crucial for sheep hair follicle development were identified, aiding fine wool breeding and human hair loss research.
research Decay of Skin-Specific Gene Modules in Pangolins
Pangolins have lost some skin-related genes, but kept others, leading to their unique scales and skin features.
research In-Silico Cardiac Aging Regulatory Model Including MicroRNA Post-Transcriptional Regulation
Researchers created a model to understand heart aging, highlighting the role of microRNAs and identifying key genes and pathways involved.
research Rodent Models in Placental Research: Implications for Fetal Origins of Adult Disease
Using rodents for research shows that health problems in the womb can cause diseases later in life.
research Sdr16c5 and Sdr16c6 Control a Dormant Pathway at a Bifurcation Point Between Meibogenesis and Sebogenesis
Sdr16c5 and Sdr16c6 genes regulate a key point in lipid production that affects eye and skin gland function.
research Studying the Genetic Predisposing Factors in the Pathogenesis of Acne Vulgaris
Genetics play a role in acne, but how exactly they contribute is not fully understood.
research Autophagy Protects Murine Preputial Glands Against Premature Aging and Controls Their Sebum Phospholipid and Pheromone Profile
Autophagy prevents early aging and maintains lipid and pheromone balance in mouse glands.
research PPAR-γ Signaling as a Key Mediator of Human Hair Follicle Physiology and Pathology
PPAR-γ is important for healthy hair and its problems, and more research on PPAR-γ treatments is needed.
research The Human Skin as a Hormone Target and an Endocrine Gland
Human skin acts like a hormone-producing organ, making and managing various hormones important for skin and hair health.
research To Grow or Not to Grow: Hair Morphogenesis and Human Genetic Hair Disorders
Genetic mutations can cause hair growth disorders by affecting key genes and signaling pathways.
research A Computationally Inferred Regulatory Heart Aging Model Including Post-Transcriptional Regulations
Researchers created a model to understand heart aging, highlighting key genes and pathways, and suggesting miR-208a as a potential heart attack biomarker.
research Inactivation of Autophagy Leads to Changes in Sebaceous Gland Morphology and Function
Autophagy is crucial for normal sebaceous gland function and sebum composition.
research Hair, Cutaneous Homeostasis, and Stem Cell Functions
Proteins like aPKC and PDGF-AA, substances like adenosine and ATP, and adipose-derived stem cells all play important roles in hair growth and health, and could potentially be used to treat hair loss and skin conditions.
research Advances in Understanding Epigenetic Regulation of Plant Trichome Development: A Comprehensive Review
Tiny RNA molecules help control the growth of plant hairs.
research Metabolic Regulation of Stem Cells in Aging
Eating less can improve stem cell function and increase lifespan.
research Sebaceous Immunobiology: Skin Homeostasis, Innate Immunity Coordination, Inflammatory Response, and Disease Associations
Sebaceous glands play a key role in skin health, immunity, and various skin diseases.
research Global Single-Cell Sequencing Landscape of Adipose Tissue of Different Anatomical Site Origin in Humans
Different parts of the body's fat tissue have unique cell types and characteristics, which could help treat chronic wounds.
research Health Risks Associated with Long-Term Finasteride and Dutasteride Use: It's Time to Sound the Alarm
Long-term use of finasteride and dutasteride can cause serious health issues like diabetes and liver problems.
research Epidermal PPARγ Is a Key Homeostatic Regulator of Cutaneous Inflammation and Barrier Function in Mouse Skin
PPARγ is essential for maintaining healthy skin, controlling inflammation, and ensuring proper skin barrier function.
research Engineered Exosomes Biopotentiated Hydrogel Promote Hair Follicle Growth via Reprogramming the Perifollicular Microenvironment
The new hydrogel treatment promotes faster hair growth and better skin health for hair loss.
research 11β-Hydroxysteroid Dehydrogenase Type 1 Inhibitors for the Treatment of Type 2 Diabetes
Inhibitors of 11β-HSD1 show potential for treating type 2 diabetes but require more testing for safety and effectiveness.