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Female mice with disrupted 5α-reductase 1 had significant metabolic issues, including stress response problems, insulin resistance, liver fat buildup, and obesity.

New understanding of the causes of primary cicatricial alopecia has led to better diagnosis and potential new treatments.

PPAR-γ is important for healthy hair and its problems, and more research on PPAR-γ treatments is needed.

Melatonin-loaded nanocarriers improve melatonin delivery and effectiveness for various medical treatments.

Lack of TG2 increases fat storage and lowers cell cleanup in skin oil cells.

Hormones and signaling pathways control sebaceous gland function and could help treat acne.

Newer low-dose oral contraceptives with less androgenic effects improve patient compliance.

The cornified cell envelope forms a protective barrier in skin and hair, using specific proteins and lipids to maintain effectiveness.

Oral contraceptives help treat hyperandrogenic disorders, improving symptoms like excessive hair and acne.

sPLA2-IIE is crucial for normal hair follicle structure and skin health.

Combining medication for dyslipidemia and insulin resistance with basic therapy improves outcomes for alopecia areata with metabolic syndrome.

Chromium supplements don't improve insulin, hormone levels, or cholesterol in women with PCOS but raise testosterone levels.

A Holstein calf in Iran with a severe genetic skin disorder was euthanized due to incurable symptoms.

The cornified envelope is crucial for skin's barrier function and involves key proteins and genetic factors.

The guide explains how to study human and mouse sebaceous glands using various staining and imaging techniques, and emphasizes the need for standardized assessment methods.

Over 67 genes linked to ichthyosis help improve diagnosis and treatment.

Scientists have found specific genes linked to different hair loss conditions, which could lead to new treatments.

Nanocarriers can improve antioxidant delivery to the skin but face safety and production challenges.

Exercise is crucial for managing polycystic ovary syndrome (PCOS) and improving overall health.

Women with PCOS in Sicily show different levels of metabolic problems depending on their PCOS type, with obesity and abnormal lipid profiles being common.

High Lipid Accumulation Product levels are linked to more hirsutism in women with Polycystic Ovary Syndrome.

The document concludes that hair loss in cats is caused by various factors, including allergies, mites, infections, and hormonal issues, with treatments varying accordingly.

Metformin helps manage PCOS by improving metabolism and ovulation, but should be part of a personalized treatment plan.

Dandruff and seborrheic dermatitis are caused by yeast feeding on scalp oils, leading to irritation and flaking.

High fasting insulin levels in women with PCOS are linked to a higher risk of heart and metabolic problems.

Understanding skin structure and development helps diagnose and treat skin disorders.

African American women have a higher risk of preterm delivery than Caucasian women, and inflammatory stimuli affect gene expression in cells related to PCOS, showing a heightened inflammatory state in women with PCOS.

Using rodents for research shows that health problems in the womb can cause diseases later in life.

Squarticles effectively deliver hair growth drugs to follicles and dermal papilla cells.

Young HS patients often have other physical and mental health issues, and research on HS covers a wide range of topics including genetics, triggers, treatments, and the need for more data.