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    Did you mean Lipid Accumulation?
    Glossary Lipid Accumulation

    excessive fat build-up within cells or tissues

    Lipid accumulation, also known as fat accumulation, refers to the build-up of lipids (fats) within cells or tissues. This process can occur in various parts of the body, including the liver, muscles, and skin, and is often associated with metabolic disorders such as obesity, diabetes, and cardiovascular diseases. In the context of hair and alopecia, excessive lipid accumulation in the scalp can potentially disrupt normal hair follicle function, contributing to hair loss.

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    1. Association between Lipid Accumulation Product and Hirsutism in Patients with Polycystic Ovary Syndrome Revista Brasileira de Ginecologia e Obstetrícia · 2016 · 1 citations
    2. 1329 Transglutaminase 2 deficiency leads to lipid accumulation and reduced autophagy in SZ95 sebocytes 2023
    3. 696 MEK and BRAF inhibitors augment the production and accumulation of sebum in hamster sebocytes Journal of Investigative Dermatology · 2016
    4. Maternal PPARγ protects nursing neonates by suppressing the production of inflammatory milk Genes & Development · 2007 · 102 citations
    5. Elevated fasting insulin is associated with cardiovascular and metabolic risk in women with polycystic ovary syndrome Diabetes and Metabolic Syndrome: Clinical Research and Reviews · 2019 · 17 citations
    6. Association between Insulin Resistance and Cardiovascular Risk Factors in Polycystic Ovary Syndrome Patients Revista Brasileira de Ginecologia e Obstetrícia · 2018 · 15 citations
    7. Parameters of obesity in polycystic ovary syndrome Journal of rare disease research & treatment · 2017 · 1 citations
    8. Clinical Usefulness of Non-Invasive Metabolic-Associated Fatty Liver Disease Risk Assessment Methods in Patients with Full-Blown Polycystic Ovary Syndrome in Relation to the MRI Examination with the Ideal IQ Sequence Biomedicines · 2022
    9. Comparative studies of the ultrastructure of the sebaceous gland Tissue and Cell · 1985 · 40 citations
    10. Integrated evaluation of umbilical cord mesenchymal stromal cell-derived extracellular vesicles across skin-related cellular and zebrafish models Frontiers in Bioengineering and Biotechnology · 2026
    11. Real-time iTRAQ-based proteome profiling revealed the central metabolism involved in nitrogen starvation induced lipid accumulation in microalgae Scientific Reports · 2017 · 73 citations
    12. 548 Deletion of Myelin Protein Zero-like 3 increases sebaceous gland size and sebocyte proliferation but reduces skin adipose depots: Can MPZL3 inhibition promote excessive loss of lipids via sebum hypersecretion? Journal of Investigative Dermatology · 2022
    13. Unravelling the link between insulin resistance and androgen excess University of Birmingham Institutional Research Archive (University of Birmingham) · 2015
    14. 녹차추출물이 인체 피지선세포주에서 지질 생성에 미치는 효과 동의생리병리학회지 = Journal of physiology & pathology in Korean Medicine · 2011
    15. Serum Metabolomics Study of Polycystic Ovary Syndrome Based on Liquid Chromatography–Mass Spectrometry Journal of Proteome Research · 2014 · 71 citations
    16. Autophagy protects murine preputial glands against premature aging, and controls their sebum phospholipid and pheromone profile Autophagy · 2021 · 6 citations
    17. Autophagy protects murine preputial glands against premature aging, and controls their sebum phospholipid and pheromone profile Figshare · 2022
    18. Effects of α-Synuclein on the Lipid Phenotype of SZ95 Human Sebocytes: A Preliminary Study in the Context of Parkinson’s Disease Cells · 2026
    19. TGFβ signaling regulates lipogenesis in human sebaceous glands cells BMC Dermatology · 2013 · 44 citations
    20. Autophagy protects murine preputial glands against premature aging, and controls their sebum phospholipid and pheromone profile Figshare · 2021
    21. Metal Accumulation in Carrots, Soil and Irrigating Water Samples Journal of Environmental Science and Engineering B · 2025
    22. Induction of ferroptosis by natural products in non-small cell lung cancer: a comprehensive systematic review Frontiers in Pharmacology · 2024 · 6 citations
    23. Sdr16c5 and Sdr16c6 control a dormant pathway at a bifurcation point between meibogenesis and sebogenesis 2023
    24. 892 Behavior of the two circulating androgens testosterone and DHEA and their main intracellular metabolites in an androgen-sensitive sebocyte cell line Journal of Investigative Dermatology · 2019
    25. Adiponectin Signaling Regulates Lipid Production in Human Sebocytes PLoS ONE · 2017 · 32 citations
    26. Cedrol mitigates hepatic lipid accumulation and adipocyte hypertrophy induced by corticosteroids through the inhibition of glucocorticoid receptor activity Scientific Reports · 2025
    27. Runx1 Role in Epithelial and Cancer Cell Proliferation Implicates Lipid Metabolism and Scd1 and Soat1 Activity Stem cells · 2018 · 24 citations
    28. Sebum Production Springer eBooks · 2016 · 1 citations
    29. Comprehensive analysis of differences in cashmere production performance in Liaoning cashmere goats by using metabolomics and transcriptomics Frontiers in Veterinary Science · 2025
    30. Prostaglandin D2 Uses Components of ROS Signaling to Enhance Testosterone Production in Keratinocytes Journal of Investigative Dermatology Symposium Proceedings · 2017 · 9 citations