TLDR Early life factors, including a mother's health and environment, can affect the chances of developing polycystic ovary syndrome later in life.
Polycystic ovary syndrome (PCOS), a prevalent endocrine disorder in women, is significantly influenced by fetal metabolic programming, which is shaped by maternal, nutritional, genetic, and environmental factors. The review identifies several factors linked to the development of PCOS, including placental pathologies, maternal metabolism, fetal hypoxia, intrauterine growth restriction, low birth weight, maternal hyperandrogenism, hyperinsulinemia, insulin resistance, and maternal exposure to plastic components like bisphenol A. The study emphasizes the importance of careful management during pregnancy to lower the risk of adolescents developing PCOS and related comorbidities in the future.
Cited in this study
6 / 6 results
68 citations
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January 2022 in “International Journal of Molecular Sciences” PCOS management includes lifestyle changes and medications, with ongoing research into repurposed drugs for better treatment options.
195 citations
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March 2020 in “Clinica Chimica Acta” High levels of male hormones, insulin resistance, and obesity are closely linked and worsen polycystic ovary syndrome, but more research is needed to improve treatments.
15 citations
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April 2018 in “Revista Brasileira de Ginecologia e Obstetrícia” Insulin resistance is common in PCOS patients and linked to obesity and increased cardiovascular risk.
135 citations
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April 2017 in “Advances in Clinical and Experimental Medicine” New treatments for PCOS show promise, including both medication and non-medication options.
1 citations
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February 2016 in “Revista Brasileira de Ginecologia e Obstetrícia” High Lipid Accumulation Product levels are linked to more hirsutism in women with Polycystic Ovary Syndrome.
26 citations
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February 2011 in “Anais Brasileiros De Dermatologia” Polycystic Ovary Syndrome can cause hair loss and skin issues, and early treatment is important for preventing complications.
