Association Between Insulin Resistance and Cardiovascular Risk Factors in Polycystic Ovary Syndrome Patients

April 2018 in “ Revista Brasileira de Ginecologia e Obstetrícia ”

Miriam da Silva Wanderley, Lara Cristina Ribeiro Pereira, Carla Karoline Jesus Santos, Vinícius Santos da Cunha, Mariam Viviane Jovino Neves

insulin resistance polycystic ovary syndrome PCOS obesity BMI waist circumference lipid accumulation product dyslipidemia arterial hypertension IR body mass index high blood pressure

TLDR Insulin resistance is common in PCOS patients and linked to obesity and increased cardiovascular risk.

The study investigated 83 polycystic ovary syndrome (PCOS) patients and found that insulin resistance (IR) was prevalent in 51.81% to 66.27% of them, with the prevalence rate varying based on the diagnostic method used. Obesity was significantly associated with a higher incidence of IR. There were also significant associations between IR and cardiovascular risk factors such as BMI, waist circumference, lipid accumulation product, dyslipidemia, and arterial hypertension. The study emphasized the importance of early detection of metabolic and cardiovascular risk factors in PCOS patients to improve their quality of life and reduce the risk of long-term complications.

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Research cited in this study

4 / 4 results

research Genetic, Hormonal, and Metabolic Aspects of PCOS: An Update

258 citations, July 2016 in “Reproductive Biology and Endocrinology”

The document concludes that insulin resistance is key in PCOS development and early treatment is crucial to prevent complications.

research Diagnosis and Treatment of Polycystic Ovary Syndrome: An Endocrine Society Clinical Practice Guideline

1265 citations, October 2013 in “The Journal of Clinical Endocrinology and Metabolism”

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Polycystic Ovary Syndrome: A Complex Condition with Psychological, Reproductive, and Metabolic Manifestations That Impacts Health Across the Lifespan

research Polycystic Ovary Syndrome: A Complex Condition with Psychological, Reproductive, and Metabolic Manifestations That Impacts Health Across the Lifespan

926 citations, June 2010 in “BMC Medicine”

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research Revised 2003 Consensus on Diagnostic Criteria and Long-Term Health Risks Related to Polycystic Ovary Syndrome (PCOS)

4025 citations, December 2003 in “Human Reproduction”

The 2003 consensus updated PCOS diagnosis criteria and linked PCOS to higher risks of diabetes and heart problems, recommending lifestyle changes to lower these risks.

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