Serum Lipid Profile and Insulin Resistance in Women with Polycystic Ovary Syndrome

The study conducted in 2018 involved 153 women with Polycystic Ovary Syndrome (PCOS) and 449 healthy women. It found that women with PCOS had a higher frequency of low HDL and high total cholesterol than the control group. However, there was no significant difference in the mean levels of total cholesterol, triglyceride, HDL cholesterol, LDL cholesterol, fasting glucose, HOMA IR, LAP, and PA between the two groups. When the results were separated based on body mass index (BMI), it was found that in women with a BMI greater than 30, the mean triglyceride and glucose levels were higher in the PCOS group than the control group. In non-obese women, the total cholesterol level was higher in patients with PCOS than healthy women. The study concluded that all patients with PCOS should be reminded of the risk of glucose metabolism disorders and recommended lifestyle modifications.