Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This study found that knocking down the gene SFRP1 in human hair follicles ex vivo prolonged the hair growth phase and increased keratinocyte proliferation, suggesting potential as a therapeutic target for maintaining hair growth in male pattern baldness, while DKK1 knockdown showed no effect.

In this study, the novel fatty acid-conjugated tetrapeptide Palmitoyl-GDPH enhanced wound healing in rats by improving re-epithelialization and collagen deposition with minimal toxicity observed at the used dosage.

This study found that intravenous transplantation of human hair follicle-derived mesenchymal stem cells improved trabecular bone mass in osteoporotic mice by enhancing bone formation and reducing bone resorption.

This study found that the ACTH/MC2R system is important for hair cycle regulation, with deficiencies in MC2R leading to altered hair growth phases in mice.

This study provides a comprehensive review of the use of electrospinning technology to create 3D porous structures for bone implants, emphasizing the synergy between biomedicine and materials science necessary for developing orthopedic materials.

In this animal study, oral administration of wedelolactone significantly improved bone mineral density and reduced osteoclast numbers in a model of particle-induced osteolysis, suggesting potential as a treatment option.

This study found that a conditioned medium from human umbilical cord mesenchymal stem cells cultured in a gelatin sponge significantly enhanced hair growth and promoted skin angiogenesis in a mouse model, more effectively than a monolayer culture.

In this ex vivo and in vitro study, researchers found that capacitive resistive electrical transfer therapy increased cell proliferation and reduced cell death in hair follicles from patients with androgenic alopecia, suggesting potential benefits for alopecia treatment.

This review examines the life cycle, biomarkers, and functions of hair follicle stem cells, emphasizing their role in hair loss therapy and other skin and hair disorders, but reports no new clinical results.

This study found that platelet-rich plasma (PRP) was more effective than minoxidil 5% topical treatment in increasing hair density for androgenic alopecia patients and had an additional benefit when combined with minoxidil.

This study found that organ-cultured human scalp hair follicles can mimic chemotherapy-induced damage in vivo and serve as a model to explore molecular targets and protective agents for hair follicle preservation.

This study demonstrates that young coconut juice appears to have estrogen-like properties that can accelerate wound healing in ovariectomized rats.

This study found that GDNF promotes hair formation and skin wound repair by enhancing the self-renewal and differentiation of bulge stem cells in mice.

This study found that 4-aminopyridine significantly enhanced skin wound healing by accelerating wound closure, improving skin architecture, and promoting hair follicle neogenesis and tissue regeneration.

Thyroid-stimulating hormone affects hair follicles but doesn't change hair growth or color.

In this study, exosome-mimetic nanovesicles derived from neural progenitor cells promoted hair follicle regeneration in mice by activating the Wnt/β-catenin signaling pathway.

In this study, researchers found that the human hair follicle microbiota vary by anatomical compartment and donor age, with specific microbes like S. epidermidis potentially influencing hair follicle functions, which suggests new avenues for therapeutic targeting.

Male and female mice have different skin thickness, and hormones affect their skin and hair growth differently.

This study observed that hair follicle mesenchyme in mice exhibits significant plasticity during the hair cycle, with cell migration and changes in papilla size impacting hair production.

This study found that DPG promoted wound healing in rat skin, with increased collagen I density, particularly evident within the first 14 days after injury.

This review discusses the composition, preparation, and applications of autologous platelet and extracellular vesicle-rich plasma, highlighting its potential benefits and the need for further research, but it reports no new clinical findings.

This article discusses the potential role of telocytes in skin regeneration and the need to understand their interaction with platelet-rich plasma, reporting no new experimental results.

This study reports that Edelweiss extract significantly prolonged the anagen phase and increased hair density, suggesting potential as an anti-hair loss treatment.

This study found that upper-bulge epidermal stem cells in mouse hair follicles are specialized for nerve interactions, crucial for forming tactile sensory units, and influence touch responses via EGFL6 and αv integrin pathways.

In this study, upper-bulge epidermal stem cells in mouse hair follicles were shown to play a role in forming tactile sensory units by creating an extracellular matrix that supports nerve interactions.

This study found that both marine and bovine collagen peptides may help prevent hair loss by supporting epithelial hair follicle stem cell functions, with marine peptides maintaining hair in the growth phase and bovine peptides increasing stem cell presence in hair follicle regions.

This study in mice found that maternal iron deficiency led to hair loss and growth abnormalities in offspring due to increased oxidative stress and disrupted signaling pathways, but postnatal iron supplementation was able to reverse these effects.

This study found that the protein Foxn1 is crucial for the development and fat-storing capacity of dermal white adipose tissue in mice, influencing both lipid metabolism and adipogenesis in the skin through Bmp2 and Igf2 signaling pathways.

mIGF-1 in skin cells speeds up wound healing and hair growth in mice without harmful effects.

This study found that ICAM-1 expression in murine skin is developmentally regulated and crucial for skin and hair follicle remodeling beyond its recognized role in immune responses.