Effectiveness of Platelet-Rich Plasma in the Treatment of Androgenic Alopecia Compared to Placebo and Topical Minoxidil: A Systematic Review

    December 2022 in “ Scientia Pharmaceutica ”
    Julia Maria Borowiecka, Bartosz Dalewski, Łukasz Pałka
    Studysummary This study found that platelet-rich plasma (PRP) was more effective than minoxidil 5% topical treatment in increasing hair density for androgenic alopecia patients and had an additional benefit when combined with minoxidil.
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    Research cited in this study 19

    1. Platelet Rich Plasma and Its Use in Hair Regrowth: A Review Drug design, development and therapy · 2022
    2. Investigating the Safety and Efficacy of Platelet-Rich Plasma Treatment for Female Androgenetic Alopecia: Review of the Literature Medicina-lithuania · 2021
    3. A Narrative Review of the Research Progress and Clinical Application of Platelet-Rich Plasma Annals of palliative medicine · 2021
    4. Comparative Evaluation of the Clinical Efficacy of PRP Therapy, Minoxidil, and Their Combination with Immunohistochemical Study of the Dynamics of Cell Proliferation in the Treatment of Men with Androgenetic Alopecia International Journal of Molecular Sciences · 2020
    5. Evaluation of Platelet-Rich Plasma as a Treatment for Androgenetic Alopecia: A Randomized Controlled Trial Journal of The American Academy of Dermatology · 2020
    6. The Effect of Platelet-Rich Plasma on Female Androgenetic Alopecia: A Randomized Controlled Trial Journal of The American Academy of Dermatology · 2020
    7. Growth Factor Concentrations in Platelet-Rich Plasma for Androgenetic Alopecia: An Intra-Subject, Randomized, Blinded, Placebo-Controlled, Pilot Study Experimental Dermatology · 2020
    8. Comparison of Efficacy of Platelet-Rich Plasma Therapy With or Without Topical 5% Minoxidil in Male-Type Baldness: A Randomized, Double-Blind Placebo Control Trial Indian Journal of Dermatology, Venereology and Leprology · 2019
    9. Treatment of Male Pattern Alopecia with Platelet-Rich Plasma: A Double-Blind Controlled Study with Analysis of Platelet Number and Growth Factor Levels Journal of The American Academy of Dermatology · 2018
    10. Mechanical and Controlled PRP Injections in Patients Affected by Androgenetic Alopecia Journal of Visualized Experiments · 2018
    11. Androgens Trigger Different Growth Responses in Genetically Identical Human Hair Follicles in Organ Culture Reflecting Their Epigenetic Diversity in Life The FASEB Journal · 2017
    12. The Effect of Autologous Activated Platelet-Rich Plasma Injection on Female Pattern Hair Loss: A Randomized Placebo-Controlled Study Journal of Cosmetic Dermatology · 2017
    13. The Effectiveness of Treatments for Androgenetic Alopecia: A Systematic Review and Meta-Analysis Journal of The American Academy of Dermatology · 2017
    14. Androgenetic Alopecia: An Update Of Treatment Options Drugs · 2016
    15. Randomized Placebo-Controlled, Double-Blind, Half-Head Study to Assess the Efficacy of Platelet-Rich Plasma on the Treatment of Androgenetic Alopecia Dermatologic Surgery · 2016
    16. The Effect of Platelet-Rich Plasma in Hair Regrowth: A Randomized Placebo-Controlled Trial Stem Cells Translational Medicine · 2015
    17. The Effect of Autologous Activated Platelet Rich Plasma Injection on Pattern Hair Loss: Clinical and Histomorphometric Evaluation BioMed Research International · 2014
    18. Prostaglandin D2 Inhibits Hair Growth and Is Elevated in Bald Scalp of Men with Androgenetic Alopecia Science Translational Medicine · 2012
    19. Enhanced Effect of Platelet-Rich Plasma Containing a New Carrier on Hair Growth Dermatologic Surgery · 2011

    Related research 7

    1. A Survey of Patient Attitudes Towards Topical Minoxidil in the Treatment of Hair Loss PubMed · 2022
    2. Sisaipho Alopecia Areata Treated With Tofacitinib and Oral Minoxidil JAAD case reports · 2022
    3. Platelet-Rich Plasma Microneedling Versus 5% Topical Minoxidil in the Treatment of Patterned Hair Loss Journal of the Egyptian Women's Dermatologic Society (Print) · 2016
    4. Disorders of Hair DeckerMed Medicine · 2013
    5. Effect of Minoxidil on Hair Growth in Androgenic Alopecia in Women PubMed · 2002
    6. Use of Topical Minoxidil Therapy for Androgenetic Alopecia in Women International Journal of Dermatology · 1993
    7. Treatment of Female Androgenetic Alopecia with Minoxidil 2% International Journal of Dermatology · 1992