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Long-term use of androgens can help manage Hereditary Angioedema (HAE) but may cause serious side effects, so alternative treatments with fewer side effects are being considered.

The Wnt/β-catenin pathway is important for body functions and diseases, and targeting it may treat conditions like cancer, but with safety challenges.

Progeroid mouse models show signs of early aging similar to humans, helping us understand aging better.

Large-scale fibronectin nanofibers help heal wounds and repair tissue in a skin model of a mouse.

Microneedles are effective for painless drug delivery and promoting wound healing and tissue regeneration.

Direct vasodilators and sympatholytic agents are still useful for certain conditions despite being less common due to side effects and newer drugs.

Potassium channel openers help form elastic fibers in arteries and can treat elastin deficiency and hypertension.

High-dose vitamin A and E with zinc improved blood sugar control and insulin function in diabetics, but may cause hair loss.

A specific RNA, circNlgn, contributes to heart damage and scarring caused by the cancer drug doxorubicin.

Hormone therapy for prostate cancer can increase heart risks, especially in men with heart conditions.

Stem cell therapy is promising for treating various health conditions, but more research is needed to understand its full potential and address challenges.

Testosterone therapy may slightly increase sexual desire in women with HSDD but lacks broad recommendation due to safety concerns and limited approval.

The Korean study confirmed that bariatric surgery is effective for weight loss in Asians.

The review concludes that innovations in regenerative medicine, tissue engineering, and developmental biology are essential for effective tissue repair and organ transplants.

Older, obese people with many COVID-19 symptoms are more likely to suffer from severe long-term COVID-19 effects.

Myotonic Dystrophy may age cells faster, and drugs that target aging could be potential treatments.

Ultrasound can help deliver genes to cells to stimulate tissue regeneration and enhance hair growth, but more research is needed to perfect the method.

Early diagnosis and hormone therapy can significantly improve outcomes for post-partum pituitary insufficiency in resource-limited settings.

A young Russian girl with Meier-Gorlin syndrome has two new mutations in the CDC6 gene.

Mesenchymal stem cells could help treat aging-related diseases better than current methods.

The conclusion is that obesity should be managed with a slow, balanced approach to diet and exercise, with medication and surgery as additional options, and education and access to care are important.

The document concludes that more research is needed to reduce frequent hospital visits, addiction medicine education improves with specific training, early breast cancer surgery findings are emerging, nipple smears are not very accurate, surgery for older melanoma patients doesn't extend life, a genetic condition in infants can often be treated with one drug, doctors are inconsistent with blood clot medication, a certain gene may protect against cell damage, muscle gene overexpression affects many other genes, and some mitochondrial genes are less active in mice with tumors.

Long COVID causes lasting symptoms and needs ongoing care.

Bald men may have a higher risk of heart disease, but baldness doesn't necessarily mean more severe heart disease.

Zinc levels and lymphocyte counts might be important in heart disease development.

Most dogs with adrenal-dependent hypercortisolism had normal blood pressure after one year of treatment or surgery.

Abusing steroids can damage your heart, muscles, reproductive system, liver, skin, and brain, and may increase the risk of Alzheimer's disease.

Different people show different symptoms for genetic diseases because of how sensitive their bodies are to small changes in important factors.

Using existing drugs for new purposes could be a cost-effective way to treat chest pain and non-clogged heart arteries, with some drugs for lung blood pressure showing promise but needing more testing.

Custom-designed implants effectively repaired skull damage in most soldiers injured in combat.